Results 51 to 60 of about 420,625 (305)

Nonlinear Subspace Clustering via Adaptive Graph Regularized Autoencoder

open access: yesIEEE Access, 2019
Most existing subspace clustering methods focus on learning a meaningful (e.g., sparse or low-rank) representation of the data. However, they have the following two problems which greatly limit the performance: 1) They neglect the intrinsic local ...
Qiang Ji   +4 more
doaj   +1 more source

Available Bandwidth Metrics for Application-Layer Reliable Multicast in Global Multi-Gigabit Networks

open access: yesProceedings of the International Conference on Applied Innovations in IT, 2020
Application layer multicast shows its efficiency when it is necessary to transmit enormous amount of data to many nodes. One of the most important issues for such kind of transmission is ”what is the criteria for path construction?”.
Kirill Karpov   +5 more
doaj   +1 more source

Towards the Future Internet - A European Research Perspective [PDF]

open access: yes, 2009
The Internet is a remarkable catalyst for creativity, collaboration and innovation, providing us today with amazing possibilities that just two decades ago would have been impossible to imagine.

core   +1 more source

The future of internet security

open access: yesUbiquity, 2002
Should common security technologies be blended with biometrics for accuracy and reliability?
openaire   +1 more source

Architecture Requirements of the Future Internet [PDF]

open access: yesProceedings of the 4th International Mobile Multimedia Communications Conference, 2008
The current Internet architecture curls around an original conversational model developed in the 1970's. New solutions were for a long-time built on that framework. However, the current architecture is not able to meet optimally challenges posed by new access technologies, applications and services any more. In this paper, the purpose is to bring a new
Frantti, Tapio   +3 more
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Future Internet Socio-Economics – Challenges and Perspectives [PDF]

open access: yes, 2008
. Socio-economics aims to understand the interplay between the society, economy, markets, institutions, self-interest, and moral commitments. It is a multidisciplinary field using methods from economics, psychology, sociology, history, and even ...
Nikander, Pekka   +15 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Home - About - Disclaimer - Privacy