Results 51 to 60 of about 420,625 (305)
Nonlinear Subspace Clustering via Adaptive Graph Regularized Autoencoder
Most existing subspace clustering methods focus on learning a meaningful (e.g., sparse or low-rank) representation of the data. However, they have the following two problems which greatly limit the performance: 1) They neglect the intrinsic local ...
Qiang Ji +4 more
doaj +1 more source
Application layer multicast shows its efficiency when it is necessary to transmit enormous amount of data to many nodes. One of the most important issues for such kind of transmission is ”what is the criteria for path construction?”.
Kirill Karpov +5 more
doaj +1 more source
Towards the Future Internet - A European Research Perspective [PDF]
The Internet is a remarkable catalyst for creativity, collaboration and innovation, providing us today with amazing possibilities that just two decades ago would have been impossible to imagine.
core +1 more source
The future of internet security
Should common security technologies be blended with biometrics for accuracy and reliability?
openaire +1 more source
Architecture Requirements of the Future Internet [PDF]
The current Internet architecture curls around an original conversational model developed in the 1970's. New solutions were for a long-time built on that framework. However, the current architecture is not able to meet optimally challenges posed by new access technologies, applications and services any more. In this paper, the purpose is to bring a new
Frantti, Tapio +3 more
openaire +2 more sources
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Future Internet Socio-Economics – Challenges and Perspectives [PDF]
. Socio-economics aims to understand the interplay between the society, economy, markets, institutions, self-interest, and moral commitments. It is a multidisciplinary field using methods from economics, psychology, sociology, history, and even ...
Nikander, Pekka +15 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source

