Results 121 to 130 of about 13,524 (286)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Synchronous resection of liver metastasis and rectal cancer by ALPPS technique [PDF]

Scripta Medica, 2016
So far, ALPPS (Associating liver and portal vein partition ligation for staged hepatectomy) operation has been performed only as an individual procedure in big specialized centers in developed countries.
Marić Zdravko, Kordić Ozren, Škrbić Velimir, Stakić Igor, Marić Nina   +4 more
doaj  

Following ALPPS the increase in future liver remnant function exceeds the increase in volume [PDF]

, 2016
Ernesto Sparrelid, Antonios Tzortzakakis, Ulrika Dahlén, Rimma Axelsson, B. Isaksson   +4 more
openalex   +1 more source

Systematic review of portal and hepatic vein embolization for future liver remnant hypertrophy: feasibility, efficacy, and surgical outcomes of sequential and simultaneous methods

, 2023
Kenichiro Araki, Ryosuke Fukushima, Kei Shibuya, Ken Shirabe   +3 more
openalex   +1 more source

Comparison of portal vein embolization (PVE) with PVE and mesenchymal stem cell application effectivity for future remnant liver volume growth in patients with primarily non-resectable colorectal liver metastases [PDF]

, 2020
Vladislav Třeška, T Skalický, Václav Liška, J Fichtl   +3 more
openalex   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Prognostic Value of the Future Liver Remnant Function Before Extensive Liver Resection in a Child with an Extremely Low Future Liver Remnant Volume

Acta Scientific Cancer Biology, 2021
Akhaladze DG, Rabaev GS, Merkulov NN, Tverdov TV, Grachev NS   +4 more
openaire   +1 more source

Surgical Strategy for Future Remnant Liver Hypertrophy: Portal Vein Embolization vs. Liver Venous Deprivation [PDF]

HPB, 2021
M. Couto, F. Gianonne, B. Guiu, F. Navarro, F. Panaro   +4 more
openaire   +1 more source

Assessment of Segmentary Hypertrophy of Future Remnant Liver after Liver Venous Deprivation: A Single-Center Study

Cancers
Background: Liver venous deprivation (LVD) is a recent radiological technique that has shown promising results on Future Remnant Liver (FRL) hypertrophy. The aim of this retrospective study is to compare the segmentary hypertrophy of the FRL after LVD and after portal vein embolization (PVE).
Al Taweel, Bader, Cassese, Gianluca, Khayat, Salah, Chazal, Maurice, Navarro, Francis, Guiu, Boris, Panaro, Fabrizio   +6 more
openaire   +3 more sources