Results 121 to 130 of about 12,593,748 (263)

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Breaking barriers: challenges faced by the older adults in accessing primary healthcare in a developing country

open access: yesBMC Geriatrics
Background Given the growing older adults, ensuring their access to primary and basic healthcare services is crucial. Older adults face significant challenges in accessing care, making the develop and implementation of targeted programs vital. This study
Vahid Yazdi-Feyzabadi   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Establishing a safe community program: a qualitative systematic literature review

open access: yesBMC Public Health
Research objective Accidents are a leading cause of preventable deaths in many countries around the world. Non-fatal but disabling health consequences account for a significant portion of the injury and harm resulting from accidents.
Nourolhoda Fakhrzad   +3 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Possible Futures

open access: yes, 2023
Paneldiskussion: Possible Futures, Teilnahme auf dem Podium in der Kaserne BeselInstitut für Theaterwissenschaft ...
Portmann, Alexandra
core  

Challenges and opportunities in financing urban primary healthcare in Iran: pathways to universal health coverage

open access: yesBMC Primary Care
Background Urban primary health care (UPHC) seeks to address the growing health needs of urban populations and improve public health outcomes. However, its implementation faces significant barriers, particularly in financing mechanisms, which often ...
Leila Zamani-Nezhad   +4 more
doaj   +1 more source

Identification of driving forces, uncertainties and future scenarios of Iran\'s environment

open access: yesسلامت و محیط, 2020
Background and Objective: Global macro trends on the one hand, and domestic trends and effective factors on the other, have put the future of the Iranchr('39')s environment in a state of uncertainty with concern.
A Rezayan Ghayehbashi, E Marzban
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Navigating the Maze of Futures Studies : A reflexive outlook

open access: yes
Emerging as a futurist and positioning oneself as such is a nuanced and difficult path to navigate. This paper explores our experiences as aspiring foresight professionals through a collaborative autoethnographic approach using our experiences and ...
Önnered, Simon,, Chichilanov, Valeriy,
core  

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