Results 111 to 120 of about 53,164 (268)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Breaking barriers: challenges faced by the older adults in accessing primary healthcare in a developing country

open access: yesBMC Geriatrics
Background Given the growing older adults, ensuring their access to primary and basic healthcare services is crucial. Older adults face significant challenges in accessing care, making the develop and implementation of targeted programs vital. This study
Vahid Yazdi-Feyzabadi   +3 more
doaj   +1 more source

Co-Experiential Futuring : where Speculative Design and Arts meet Futures Studies

open access: yes
In the face of continuous transformations in organisations, technological advancements directly impact the practice of professionals who need to (re)imagine and (re)shape their roles, workflows, and contexts.
Aranda Muñoz, Alvaro,   +5 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Principle Concepts in Futures Studies: A Narrative Review

open access: yesHealth Technology Assessment in Action
Context: Our world is characterized by a dynamic landscape of variations, complexities, uncertainties, and ambiguities (VUCA). These elements manifest in various domains, including politics, economics, communication, information, science, and research ...
Zahra Heydari Fard   +2 more
doaj  

Establishing a safe community program: a qualitative systematic literature review

open access: yesBMC Public Health
Research objective Accidents are a leading cause of preventable deaths in many countries around the world. Non-fatal but disabling health consequences account for a significant portion of the injury and harm resulting from accidents.
Nourolhoda Fakhrzad   +3 more
doaj   +1 more source

The futures of cultures

open access: yes, 1994
168 p., ref. bib. : dissem.This publication presents a synthesis of the results of the project "The Futures of Cultures". One of the aims of the project was to identify, at the regional and interregional levels, emergent trends and foreseeable changes in
UNESCO, Division of Studies and Programming (BEP/BP),
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Iranian university students’ alcohol-related knowledge, attitude, and practice questionnaire (ISKAP alcohol Q): development and psychometric properties

open access: yesBMC Psychology
Introduction Given the strict prohibition of alcohol use in certain religions, such as Islam, and the criminalization of its production, distribution, and consumption in a country like Iran, it becomes essential to utilize a standardized and culturally ...
Mahsa Janati   +6 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Home - About - Disclaimer - Privacy