Results 1 to 10 of about 6,710 (185)
Exploring the mechanisms of neurotoxicity caused by fuzi using network pharmacology and molecular docking [PDF]
Frontiers in Pharmacology, 2022 Safety has always been an important issue affecting the development of traditional Chinese medicine industry, especially for toxic medicinal materials, the establishment of risk prevention and control measures for toxic herbs is of great significance to ...
Junsha An +5 more
doaj +2 more sources
Frontiers in Pharmacology, 2021 Background: As time evolved, traditional Chinese medicine (TCM) became integrated into the global medical system as complementary treatments. Some essential TCM herbs started to play a limited role in clinical practices because of Western medication ...
Chi-Jung Tai +2 more
exaly +3 more sources
Heliyon, 2023 Rationale and objectives: Fuzi, the dried root of Aconitum carmichaelii Debx, is one of the widely used traditional Chinese medicines. Fuzi polysaccharides are considered the most bioactive compounds with immunomodulatory functions, however, the ...
Ran Tu
exaly +3 more sources
Fuzi alleviates cold-related rheumatoid arthritis via regulating gut microbiota and microbial bile acid metabolism [PDF]
Chinese MedicineBackground Rheumatoid arthritis (RA) with cold pattern is an important type of RA according to the theory of traditional Chinese medicine. Fuzi (also known as the lateral roots of Aconitum carmichaelii Debx.) represents a typical traditional Chinese ...
Juan Liu +5 more
doaj +2 more sources
Benefit-risk assessment of the use of toxic botanical drugs in superiority field: a case study on Aconitum carmichaeli Debx [PDF]
Frontiers in PharmacologyObjectiveThe study aimed to establish a benefit-risk assessment (BRA) model utilizing multi-criteria decision analysis (MCDA), in order to evaluate the benefit-risk relationship of decoctions containing Aconitum carmichaeli Debx.
Xiaomeng Zhang +5 more
doaj +2 more sources
Frontiers in Pharmacology, 2022 Fuzi is a famous toxic traditional herbal medicine, which has long been used for the treatment of various diseases in China and many other Asian countries because of its extraordinary pharmacological activities and high toxicity.
Zhang Wang, Tingting Kuang, Xianli Meng
exaly +3 more sources
Toxicological landscape of Fuzi: a comprehensive study on the spatial distribution of toxicants and regional neurotoxicity variability in zebrafish [PDF]
Frontiers in PharmacologyFuzi, a Chinese herb widely used in clinical settings, exhibits varying levels of toxicity depending on its geographical origin. Diester-type alkaloids are the primary contributors to the toxicity of Fuzi.
Xiaoqi Pan +6 more
doaj +2 more sources
Toxins, 2018 The processed lateral root of Aconitum carmichaelii Deb (Aconiti Radix lateralis praeparata or Fuzi) is a potent traditional herbal medicine extensively used in treatment of cardiovascular diseases, rheumatism arthritis, and bronchitis in many Asian ...
Mengbi Yang, Zhong Zuo
exaly +3 more sources
Deciphering structure-composition-efficacy transformation in processed Fuzi: an integrated SEM, XRD, metabolomics, and pharmacodynamics approach [PDF]
Frontiers in ChemistryBackgroundAconiti Lateralis Radix Praeparata (Fuzi), a vital yet toxic herbal medicine, faces significant challenges in standardization due to varied processing methods that undermine detoxification efficacy and hinder therapeutic optimization.MethodsAn ...
Yang Yang +11 more
doaj +2 more sources
Scientific Reports, 2021 In recent decades, herbal medicines have played more and more important roles in the healthcare system in the world because of the good efficacy. However, with the increasing use of herbal medicines, the toxicity induced by herbal medicines has become a ...
Wuwen Feng +5 more
doaj +2 more sources