Results 101 to 110 of about 14,829 (309)

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

Reversing Macrophage Immunometabolic Dysfunction in Prolonged Infections Via a Glutaminolysis‐Fueled Restoration‐Based Hierarchically Selective Therapeutic System

Advanced Science, EarlyView.
A hierarchically selective immunotherapeutic nanoplatform, mGls@HEV‐MTP, selectively restores macrophage immunocompetence through GLS1‐mediated restoration of glutaminolysis‐fueled anaplerosis. Concurrently, it renders Staphylococcus aureus (S. aureus) more readily recognizable to the metabolically reprogrammed macrophages, thereby facilitating ...
Weinan Yang, Zihao An, Honglu Cai, Congsun Li, Jiaxuan Zou, Wushi Cui, Wentao Chen, Tao Zhang, Shicheng Wang, Zizhan Su, Jian Xiao, Tao Sun, Bin Hu, Min Cheng, Zhongru Gou, Jianbin Xu, An Liu, Haobo Wu   +17 more
wiley   +1 more source

Study on well logging reservoir fluid evaluation method based on 2D cloud model: A case study of Kuqa Depression, Tarim Basin

Youqicang pingjia yu kaifa
Accurate interpretation of well logging data is crucial for the evaluation of reservoir fluid properties in oil and gas exploration. Conventional well logging methods rely on petrophysical models that correlate parameters such as porosity, permeability ...
WANG SHULI, WANG JINGUO, ZHANG CHENGSEN, ZHANG ZHEAN, PARHAT KAYSAR, LIU LONGCHENG   +5 more
doaj  

Social Fuzziology: Study of Fuzziness of Social Complexity [PDF]

, 2005
A review of Social Fuzziology: Study of Fuzziness of Social Complexity, by Vladimir Dimitrov and Bob Hodge, 2002. New York: Springer-Verlag, 188pp. ISBN 3798015063.
Vargas, S. Claudia
core   +1 more source

Force‐Electric Nanotentacles of Tantalum Implant Accelerate Cellular Energy Metabolism/Crosstalk for Immunomodulation‐Vascularized Bone Integration

Advanced Science, EarlyView.
A biomimetic force‐electric nanotentacle‐enabled tantalum (Ta) implant with surface‐nanostructured LiTaO3 (n‐LiTaO3) was first developed via laser nanofabrication combined with Li+‐induced in situ reaction, enabling the transduction of ultrasound into bioelectrical cues.
Taixing Zhang, Ke Ma, Kangqing Zuo, Pandong Lin, Tailong Zhang, Rongliang Ding, Linbo Zhang, Aonan Li, Yinchuan Wang, Yanling Huang, Jichao Feng, Guiyong Xiao, Yupeng Lu, Bing Han, Zhiqiang Wang, Ningbo Li   +15 more
wiley   +1 more source

Fuzziness measurement of fuzzy sets and its application in cluster validity analysis

, 2007
To measure the fuzziness of fuzzy sets, this paper introduces a distance-based and a fuzzy entropybased measurements. Then these measurements are generalized to measure the fuzziness of fuzzy partition, namely partition fuzziness.
Li, J, Li, X, Gao, X, Tao, D
core  

Probing the Energy Landscape of α‐Synuclein Amyloid Fibril Formation by Systematic K‐to‐Q Mutagenesis

Advanced Science, EarlyView.
We use lysine‐to‐glutamine mutations to study the effect of electrostatics on the kinetics and thermodynamics of alpha‐synuclein amyloid fibril formation. We find that mutational effects map on their structural context within fibrils and identify residues that modulate the energy landscape of alpha‐synuclein self‐assembly. Our work outlines a scalable,
Antonin Kunka, Azad Farzadfard, Jacob Aunstrup Larsen, Rasmus Krogh Norrild, Federica Saraceno, Celia Fricke, Hossein Mohammad‐Beigi, Ahmed Sadek, Jonas Folke, Susana Aznar, Alexander K. Buell   +10 more
wiley   +1 more source

A Study of Pragmatic Functions of Fuzziness in News Reports from the Perspective of Adaptation Theory

, 2018
Accuracy is one of the biggest features of news reports, but in fact, we often note that news reports will use a lot of fuzziness, which plays an important role in these news reports.
Yun Lian
core   +1 more source

MAPA: A Semantic Network Framework for Functional Module Discovery and Interpretation in Multi‐Omics Data

Advanced Science, EarlyView.
MAPA transforms complex multi‐omics data into biologically coherent functional modules by integrating pathway information with molecular interaction networks. Retrieval‐augmented large language models then generate structured, literature‐informed interpretations.
Yifei Ge, Feifan Zhang, Yijiang Liu, Chao Jiang, Peng Gao, Nguan Soon Tan, Sai Zhang, Yuchen Shen, Qianyi Zhou, Xin Zhou, Xiao Wang, Fangqing Zhao, Chuchu Wang, Xiaotao Shen   +13 more
wiley   +1 more source

Two-Dimensional Fuzzy Spatial Relations: A New Way of Computing and Representation

Advances in Fuzzy Systems, 2012
Fuzziness is found everywhere, in modeling spatial relations, fuzziness is found at object level as well as in relation semantics. Commonly, fuzzy topological relations are computed between fuzzy objects. Fuzziness in relation semantics is represented by
Nadeem Salamat, El-hadi Zahzah
doaj   +1 more source