Results 151 to 160 of about 77,938 (282)

His‐MMDM: Multi‐Domain and Multi‐Omics Translation of Histopathological Images with Diffusion Models

open access: yesAdvanced Science, EarlyView.
His‐MMDM is a diffusion model‐based framework for scalable multi‐domain and multi‐omics translation of histopathological images, enabling tasks from virtual staining, cross‐tumor knowledge transfer, and omics‐guided image editing. ABSTRACT Generative AI (GenAI) has advanced computational pathology through various image translation models.
Zhongxiao Li   +13 more
wiley   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

open access: yesAdvanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang   +7 more
wiley   +1 more source

Polarization‐Dependent 3D Holography Generated by Inverse Design Nanoprinting Metasurface

open access: yesAdvanced Science, EarlyView.
A novel polarization‐dependent 3D holography is proposed by introducing polarization as an additional freedom, enabling enhanced depth selectivity and greater control over holographic reconstruction. The efforts perfectly combine the polarization and 3D holography display into ADAM gradient descent algorithm, the application of nanoprinting further ...
Lingxing Xiong   +7 more
wiley   +1 more source

Surface Graphitized Mesoporous Carbon Surpasses the Conductivity–Porosity Trade‐Off

open access: yesAdvanced Science, EarlyView.
Electrochemical cathodic polarization in molten CaCl2‐NaCl converts mesoporous carbon (MC) into surface‐graphitized mesoporous graphite, simultaneously increasing surface area (397–867 m2/g) and electrical conductivity (26–450 S/cm) without mass loss.
Juntian Fan   +12 more
wiley   +1 more source

Neural Fields for Highly Accelerated 2D Cine Phase Contrast MRI

open access: yesAdvanced Science, EarlyView.
ABSTRACT 2D cine phase contrast (CPC) MRI provides quantitative information on blood velocity and flow within the human vasculature. However, data acquisition is time‐consuming, motivating the reconstruction of the velocity field from undersampled measurements to reduce scan times. In this work, neural fields are proposed as a continuous spatiotemporal
Pablo Arratia   +7 more
wiley   +1 more source

SAGE: Spatially Aware Gene Selection and Dual‐View Embedding Fusion for Domain Identification in Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
SAGE is a unified framework for spatial domain identification in spatial transcriptomics that jointly models tissue architecture and gene programs. Topic‐driven gene selection (NMF plus classifier‐based scoring) highlights spatially informative genes, while dual‐view graph embedding fuses local expression and non‐local functional relations.
Yi He   +5 more
wiley   +1 more source

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