Integrated Engineering of CAR‐T Cells for Solid Tumours
Solid tumours pose multifactorial barriers including antigen heterogeneity, immunosuppressive microenvironment, and poor T‐cell trafficking, limiting CAR‐T efficacy compared to hematologic malignancies. Integrated engineering strategies are essential, combining logic‐gated receptors for precision, metabolic‐epigenetic reprogramming for resilience, and ...
Chao Yang +5 more
wiley +1 more source
An innovative fuzzy model control strategy for Trans-Z-Source DC-DC boost converters in satellite power systems. [PDF]
Lotfy MW +3 more
europepmc +1 more source
Recent advances in the genomics of sugarcane (Saccharum)
This review systematically summarizes advances in sugarcane genomics, evolution, classification, and breeding practices. It identifies key research bottlenecks and proposes an integrated research framework to facilitate predictive sugarcane breeding, which provides valuable references for genetic improvement of other complex polyploid crops.
Tianyou Wang +5 more
wiley +1 more source
Fuzzy logic-based speed guidance strategy for mixed platoons at intersections with communication delay compensation and driver reaction time modeling. [PDF]
Liu X, Yan M, Dai R, Gao M.
europepmc +1 more source
Carotid artery dissection linked to intermittent apnoeic swimming: A case–control study
Abstract Internal carotid artery (ICA) dissection is a rare and potentially devastating cause of cerebral ischaemia, initiated by an intimal tear or rupture of the vasa vasorum, that can lead to an intraluminal thrombus, vascular stenosis, occlusion, or dissecting aneurysm formation.
Damian M. Bailey +14 more
wiley +1 more source
Optimizing wireless sensor networks using fuzzy triangular snake graph models and fuzzy topological indices. [PDF]
Hashem AF, Liaqat S, Mufti ZS, Hanif MF.
europepmc +1 more source
Schematic diagram of the whale optimization algorithm (WOA)–optimized fuzzy proportional–integral–derivative (PID) controller. The WOA is employed to dynamically tune the scaling factor expressions and fuzzy control parameters (a(e)a(e), a(ec)a(ec), βpβp, βiβi), as well as the initial PID gains (kp0kp0, ki0ki0), based on the error (ee) and its ...
Xiaosong Tian +7 more
wiley +1 more source
Why family medicine requires a paradigm shift from linear guidelines to complexity science. [PDF]
İnan M, Aypak C.
europepmc +1 more source
Fish Scales: A Multifunctional Biomaterial from Nature
Fish scales demonstrate nature's solution to impact protection through overlapping multilayered architecture. This biological design combines mineralized surfaces with collagen networks to achieve both flexibility and fracture resistance. The structural principles inspire advanced protective materials and biomedical implants, where damage tolerance ...
Liyao Dong, Xiaojie Sun, Xiguang Chen
wiley +1 more source
Fog computing based cost optimization for university governance. [PDF]
Tian Q, Li G.
europepmc +1 more source

