Results 151 to 160 of about 717,766 (291)

POINTED GENERALIZED TOPOLOGICAL SPACES

open access: yes四川大学学报. 自然科学版, 1986
Instead of locales without points and neighborhood structures,we setup a theory of pointed generalized topology,which contains point settopology,fuzzy topology and spatial locales as special cases .
He Ming
doaj  

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

open access: yesSmart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin   +10 more
wiley   +1 more source

From Patterns to Attractor‐Like Modes: A Systems Sensemaking Framework for Recurring Conflict in Healthcare Teams

open access: yesSystems Research and Behavioral Science, EarlyView.
ABSTRACT Recurring conflict in healthcare teams frequently persists despite well‐intended interventions (Page et al. 2024; Mazzei et al. 2024). Dynamic systems theory helps to map how such recurrences reflect systemic feedback loops linking individual experience, behaviour, shared beliefs and organisational structures, supporting intervention design at
Dominik Havsteen‐Franklin
wiley   +1 more source

AI‐enabled bumpless transfer control strategy for legged robot with hybrid energy storage system

open access: yesCAAI Transactions on Intelligence Technology, EarlyView.
Abstract Designing Hybrid energy storage system (HESS) for a legged robot is significant to improve the motion performance and energy efficiency of the robot. However, switching between the driving mode and regenerative braking mode in the HESS may generate a torque bump, which has brought significant challenges to the stability of the robot locomotion.
Zhiwu Huang   +6 more
wiley   +1 more source

Classification of Broadband Oscillations Using Wavelet Convolution and Multi‐Channel Attention Network

open access: yesEnergy Internet, EarlyView.
ABSTRACT Accurate identification of broadband oscillation types is a prerequisite for implementing appropriate control strategies. The strongly nonlinear, nonstationary and multi‐modal characteristics of broadband oscillation signals impose higher demands on identification methods. Practical applications face challenges such as coupling effects between
Jinduo Yang   +7 more
wiley   +1 more source

Fuzzy Topologies and Fuzzy Topological Vector Spaces

open access: yesJournal of Japan Society for Fuzzy Theory and Systems, 1994
openaire   +2 more sources

Rosemary metabolite carnosic acid opens Kv1.1 via its voltage sensor and corrects Kv1.1‐linked episodic ataxia in mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder caused primarily by loss‐of‐function mutations in the voltage‐gated potassium channel Kv1.1 (KCNA1). Small molecules that restore Kv1.1 activity hold promise as targeted therapies for EA1, yet current pharmacological strategies remain limited ...
Rían W. Manville   +6 more
wiley   +1 more source

FluidMap: Proportional and Spatially Consistent Layout Enrichments in Multidimensional Projections

open access: yesComputer Graphics Forum, EarlyView.
FluidMap faithfully represents the frequency of an attribute and preserves spatial consistency. Current space‐filling methods over‐ or under‐represent attribute categories (i.e., all Voronoi‐based methods), sacrifice spatial consistency (i.e., Nmap) or both (i.e., Voronoi‐MWα).
Daniela Blumberg   +5 more
wiley   +1 more source

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