Results 11 to 20 of about 18,655 (153)

Towards the Experimentally-Informed In Silico Nozzle Design Optimization for Extrusion-Based Bioprinting of Shear-Thinning Hydrogels

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Research in bioprinting is booming due to its potential in addressing several manufacturing challenges in regenerative medicine. However, there are still many hurdles to overcome to guarantee cell survival and good printability.
Esther Reina-Romo   +10 more
doaj   +2 more sources

Mapping the use of computational modelling and simulation in clinics: A survey

open access: yesFrontiers in Medical Technology, 2023
In silico medicine describes the application of computational modelling and simulation (CM&S) to the study, diagnosis, treatment or prevention of a disease. Tremendous research advances have been achieved to facilitate the use of CM&S in clinical
Raphaëlle Lesage   +10 more
doaj   +2 more sources

Towards in silico Models of the Inflammatory Response in Bone Fracture Healing

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
In silico modeling is a powerful strategy to investigate the biological events occurring at tissue, cellular and subcellular level during bone fracture healing.
Laura Lafuente-Gracia   +11 more
doaj   +2 more sources

Time variable effectiveness and cost-benefits of different nature-based solution types and design for drought and flood management

open access: yesNature-Based Solutions, 2023
Nature Based Solutions (NBS) for water resources management have potential to mitigate climate change impacts, including more frequent flooding and droughts.
Jessica Fennell   +4 more
doaj   +2 more sources

Use of Computational Modeling to Study Joint Degeneration: A Review

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Osteoarthritis (OA), a degenerative joint disease, is the most common chronic condition of the joints, which cannot be prevented effectively. Computational modeling of joint degradation allows to estimate the patient-specific progression of OA, which can
Satanik Mukherjee   +6 more
doaj   +2 more sources

A flexible and easy-to-use open-source tool for designing functionally graded 3D porous structures

open access: yesVirtual and Physical Prototyping, 2022
Advances in additive manufacturing technologies are leading to an increased interest in the design of intricate 3D geometries for applications ranging from aerospace to biomedical engineering. In this paper, we present ASLI (A Simple Lattice Infiller), a
Fernando Perez-Boerema   +2 more
doaj   +2 more sources

Position Paper From the Digital Twins in Healthcare to the Virtual Human Twin: A Moon-Shot Project for Digital Health Research [PDF]

open access: yesIEEE journal of biomedical and health informatics, 2023
The idea of a systematic digital representation of the entire known human pathophysiology, which we could call the Virtual Human Twin, has been around for decades.
M. Viceconti   +3 more
semanticscholar   +1 more source

Scientific and regulatory evaluation of mechanistic in silico drug and disease models in drug development: Building model credibility

open access: yesCPT: Pharmacometrics & Systems Pharmacology, 2021
The value of in silico methods in drug development and evaluation has been demonstrated repeatedly and convincingly. While their benefits are now unanimously recognized, international standards for their evaluation, accepted by all stakeholders involved,
F. Musuamba   +19 more
semanticscholar   +1 more source

The ‘Digital Twin’ to enable the vision of precision cardiology

open access: yesEuropean Heart Journal, 2020
Providing therapies tailored to each patient is the vision of precision medicine, enabled by the increasing ability to capture extensive data about individual patients.
Jorge Corral-Acero   +38 more
semanticscholar   +1 more source

Autorystės pasisavinimo nusikaltimo objektas ir jo reikšmė veikai kvalifikuoti [PDF]

open access: yes, 2020
This article analyses one element of corpus delicti of misappropriation of authorship, criminalised in Lithuanian Criminal Code Article 191 – the object (or the protected good) of a crime.
Steponavičiūtė, Ramunė
core   +2 more sources

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