Results 1 to 10 of about 81,756 (163)
Toward the Next Generation of In Silico Modeling of Dynamic Host-Microbiota Interactions in the Skin [PDF]
JID InnovationsUnderstanding how the skin microbiota contributes to skin health and disease requires knowledge of the dynamic interactions between the skin and its resident microbes.
Jamie Lee +6 more
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Frontiers in Physiology, 2023 Intracardiac electrograms (iEGMs) are time traces of the electrical potential recorded close to the heart muscle. We calculate unipolar and bipolar iEGMs analytically for a myocardial slab with parallel myofibers and validate them against numerical ...
Lore Leenknegt +4 more
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Application in silico Modeling Simulation in Bioequivalence Studies: A Review
Journal of Food and Pharmaceutical Sciences, 2023 Bioequivalence testing aims to ensure that the therapeutic performance of the drug is consistent and reproducible when it is administrated. Modeling and simulation in silico methods are currently performed to conduct virtual bioequivalence studies ...
Sekar Ayu Pawestri
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In Silico Hemostasis Modeling and Prediction [PDF]
Hämostaseologie, 2020 AbstractComputational physiology, i.e., reproduction of physiological (and, by extension, pathophysiological) processes in silico, could be considered one of the major goals in computational biology. One might use computers to simulate molecular interactions, enzyme kinetics, gene expression, or whole networks of biochemical reactions, but it is (patho)
Dmitry Y, Nechipurenko +3 more
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Plant catalase in silico characterization and phylogenetic analysis with structural modeling
Journal of Genetic Engineering and Biotechnology, 2022 Background Catalase (EC 1.11.1.6) is a heme-containing tetrameric enzyme that plays a critical role in signaling and hydrogen peroxide metabolism. It was the first enzyme to be crystallized and isolated. Catalase is a well-known industrial enzyme used in
Takio Nene +2 more
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Modeling Neurodegeneration in silico With Deep Learning [PDF]
Frontiers in Neuroinformatics, 2021 Deep neural networks, inspired by information processing in the brain, can achieve human-like performance for various tasks. However, research efforts to use these networks as models of the brain have primarily focused on modeling healthy brain function so far.
Anup Tuladhar +13 more
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In silico modelling of DNA nanostructures
Computational and Structural Biotechnology Journal, 2020 The rise of material science and nanotechnology created a demand for a next generation of materials and procedures that can transcend the shaping of simple geometrical nano-objects. As a legacy of the technological progress made in the Human Genome Project, DNA was identified as a possible candidate.
Kekic, Tadija, Barisic, Ivan
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In silico imaging clinical trials: cheaper, faster, better, safer, and more scalable
Trials, 2021 Imaging clinical trials can be burdensome and often delay patient access to novel, high-quality medical devices. Tools for in silico imaging trials have significantly improved in sophistication and availability.
Aldo Badano
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Drug Delivery, 2022 Transdermal fentanyl patches are an effective alternative to the sustained release of oral morphine for chronic pain management. Due to the narrow therapeutic range of fentanyl, the concentration of fentanyl in the blood needs to be carefully monitored ...
Flora Bahrami +2 more
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Critical Care Medicine, 2013 To familiarize clinicians with advances in computational disease modeling applied to trauma and sepsis.PubMed search and review of relevant medical literature.Definitions, key methods, and applications of computational modeling to trauma and sepsis are reviewed.Computational modeling of inflammation and organ dysfunction at the cellular, organ, whole ...
Yoram, Vodovotz, Timothy R, Billiar
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