Results 1 to 10 of about 167,660 (149)
Toward the Next Generation of In Silico Modeling of Dynamic Host-Microbiota Interactions in the Skin [PDF]
JID InnovationsUnderstanding how the skin microbiota contributes to skin health and disease requires knowledge of the dynamic interactions between the skin and its resident microbes.
Jamie Lee +6 more
doaj +4 more sources
Frontiers in Physiology, 2023 Intracardiac electrograms (iEGMs) are time traces of the electrical potential recorded close to the heart muscle. We calculate unipolar and bipolar iEGMs analytically for a myocardial slab with parallel myofibers and validate them against numerical ...
Lore Leenknegt +4 more
doaj +1 more source
Application in silico Modeling Simulation in Bioequivalence Studies: A Review
Journal of Food and Pharmaceutical Sciences, 2023 Bioequivalence testing aims to ensure that the therapeutic performance of the drug is consistent and reproducible when it is administrated. Modeling and simulation in silico methods are currently performed to conduct virtual bioequivalence studies ...
Sekar Ayu Pawestri
doaj +1 more source
Plant catalase in silico characterization and phylogenetic analysis with structural modeling
Journal of Genetic Engineering and Biotechnology, 2022 Background Catalase (EC 1.11.1.6) is a heme-containing tetrameric enzyme that plays a critical role in signaling and hydrogen peroxide metabolism. It was the first enzyme to be crystallized and isolated. Catalase is a well-known industrial enzyme used in
Takio Nene +2 more
doaj +1 more source
Fluctuating Nonlinear Spring Model of Mechanical Deformation of Biological Particles [PDF]
, 2015 We present a new theory for modeling forced indentation spectral lineshapes of biological particles, which considers non-linear Hertzian deformation due to an indenter-particle physical contact and bending deformations of curved beams modeling the ...
Gijs J L Wuite +6 more
core +7 more sources
In silico imaging clinical trials: cheaper, faster, better, safer, and more scalable
Trials, 2021 Imaging clinical trials can be burdensome and often delay patient access to novel, high-quality medical devices. Tools for in silico imaging trials have significantly improved in sophistication and availability.
Aldo Badano
doaj +1 more source
Drug Delivery, 2022 Transdermal fentanyl patches are an effective alternative to the sustained release of oral morphine for chronic pain management. Due to the narrow therapeutic range of fentanyl, the concentration of fentanyl in the blood needs to be carefully monitored ...
Flora Bahrami +2 more
doaj +1 more source
Continuum Modeling and Simulation in Bone Tissue Engineering [PDF]
, 2019 Bone tissue engineering is currently a mature methodology from a research perspective. Moreover, modeling and simulation of involved processes and phenomena in BTE have been proved in a number of papers to be an excellent assessment tool in the stages ...
Reina Romo, Esther +1 more
core +1 more source
Agent-based computational modeling of wounded epithelial cell monolayers [PDF]
, 2004 Computational modeling of biological systems, or ‘in silico biology’ is an emerging tool for understanding structure and order in biological tissues. Computational models of the behavior of epithelial cells in monolayer cell culture have been developed ...
Hill, G. +4 more
core +1 more source
AIP Advances, 2020 Recent improvements in computational tools opened the possibility of patient-specific modeling to aid clinicians during diagnosis, treatment, and monitoring. One example is the modeling of blood flow for surgical planning, where modeling can help predict
Ana Paula Narata +8 more
doaj +1 more source