Results 21 to 30 of about 114,431,160 (255)
The acceptance of
, 2011 In silico models have prompted considerable interest and debate because of their potential value in predicting the properties of chemical substances for regulatory purposes.
Antonio Cassano +31 more
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In-silico modeling of granulomatous diseases [PDF]
Current Opinion in Pulmonary Medicine, 2016 The pathogenesis of genetically complex granulomatous diseases, such as sarcoidosis and latent tuberculosis, remains largely unknown. With the recent advent of more powerful research tools, such as genome-wide expression platforms, comes the challenge of making sense of the enormous data sets so generated. This manuscript will provide demonstrations of
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Semantically Linking in Silico Cancer Models [PDF]
Cancer Informatics, 2014 Multiscale models are commonplace in cancer modeling, where individual models acting on different biological scales are combined within a single, cohesive modeling framework. However, model composition gives rise to challenges in understanding interfaces and interactions between them.
Johnson, D +6 more
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Ethics in autonomous robots as philosophy in silico: The study case of phronetic machine ethics
Logos i Ethos, 2020 The paper explores the application of computing science to the modeling of the ethical concepts. The modeling in computers is denoted as in silico modeling.
Paweł Polak, Roman Krzanowski
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In silico modelling of DNA nanostructures
Computational and Structural Biotechnology Journal, 2020 The rise of material science and nanotechnology created a demand for a next generation of materials and procedures that can transcend the shaping of simple geometrical nano-objects. As a legacy of the technological progress made in the Human Genome Project, DNA was identified as a possible candidate.
Kekic, Tadija, Barisic, Ivan
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In silico Models of Alcohol Dependence and Treatment [PDF]
Frontiers in Psychiatry, 2012 In this paper we view alcohol dependence and the response to treatment as a recurrent bio-behavioral process developing in time and propose formal models of this process combining behavior and biology in silico. The behavioral components of alcohol dependence and treatment are formally described by a stochastic process of human behavior, which serves ...
Kovatchev, Boris +2 more
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Modeling and evolving biochemical networks: insights into communication and computation from the biological domain [PDF]
, 2008 This paper is concerned with the modeling and evolving of Cell Signaling Networks (CSNs) in silico. CSNs are complex biochemical networks responsible for the coordination of cellular activities.
J. Decraene +5 more
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BCNNM: A Framework for in silico Neural Tissue Development Modeling [PDF]
, 2021 Cerebral (“brain”) organoids are high-fidelity in vitro cellular models of the developing brain, which makes them one of the go-to methods to study isolated processes of tissue organization and its electrophysiological properties, allowing to collect ...
Kolchanova, Sofiia M., +13 more
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In-Silico Trials for Treatment of Acute Ischemic Stroke
Frontiers in Neurology, 2020 Despite improved treatment, a large portion of patients with acute ischemic stroke due to a large vessel occlusion have poor functional outcome. Further research exploring novel treatments and better patient selection has therefore been initiated.
Praneeta R. Konduri +7 more
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In silico modeling in infectious disease
Drug Discovery Today: Disease Models, 2007 Infectious disease has witnessed the emergence of mathematical modeling a tool of synthesizing data of growing complexity now available to clinicians and basic scientists alike. The purpose of this review is to introduce mathematical tools commonly used to model infectious disease.
Daun, Silvia, Clermont, Gilles
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