Results 71 to 80 of about 830,970 (279)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Designing a dexterous reconfigurable packaging system for flexible automation [PDF]

open access: yes, 2003
This paper presents a design for a reconfigurable packaging system that can handle cartons of different shape and sizes and is amenable to ever changing demands of packaging industries for perfumery and cosmetic products.
Crowder, Richard M., Dubey, Venketesh N.
core   +1 more source

DETEKSI ERROR PADA REGESTER GESER TINGKAT n-k

open access: yesJurnal Masyarakat Informatika, 2010
A transmitted code vector may be perturbed by noise, then the vector received may be a corrupted version of the transmitted code vector. A codeword with polynomial representation  U(X) is transmitted and Z(X)  is the corrupted version of V(X), then it ...
Suhartono Suhartono
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Relationship among diseases of the nervous- and circulatory systems, hospital length of stay and functional gain of patients in a private sub-acute hospital, Gauteng, South Africa

open access: yesSouth African Journal of Occupational Therapy
Introduction: This study aimed to determine if a relationship between average length of stay of patients diagnosed with diseases of the nervous system (ICD-10 code G) and of the circulatory system (ICD-10 code I) and their functional gains private sub ...
Elmarie Broodryk   +3 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

A Maintainability Framework to Ensure the Software Quality in Object-Oriented Programming

open access: yesIEEE Access
In recent years, there have been significant challenges in the attempt to improve modular structure and code reusability in software development. Software developers should ensure that refactoring not only eliminates code smells but also leads to ...
Siti Rochimah   +5 more
doaj   +1 more source

DESIGNING A G CODE PROGRAMMING LANGUAGE FOR THE REFERENCE POINT SEVEN-SPEED SHAFT [PDF]

open access: yesFiabilitate şi Durabilitate, 2015
A CNC machine makes use of mathematics and various coordinate systems to understand and process the information it receives to determine what to move where and how fast . The most important function of any CNC machine is precise and rigorous control of
VALERIA VICTORIA IOVANOV
doaj  

Special identity subgraph in genetic code [PDF]

open access: yesNetwork Biology, 2022
The genetic code is a series of codons that stores genetic information about protein molecule formation. The identity graph of a group G is a graph in which the vertex set is the set of all elements of the group and two vertices in G are adjacent if a.b =
Birinchi Kumar Boruah, Tazid Ali
doaj  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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