Results 121 to 130 of about 14,713,178 (309)
Multicritical matrix models and the chiral phase transition [PDF]
, 1998 Universality of multicritical unitary matrix models is shown and a new scaling behavior is found in the microscopic region of the spectrum, which may be relevant for the low energy spectrum of the Dirac operator at the chiral phase ...
Akemann, G, Akemann, Gernot, G. Akemann
core +1 more source
On the spectral radius and energy of the degree distance matrix of a connected graph
Open MathematicsLet GG be a simple connected graph on nn vertices. The degree of a vertex v∈V(G)v\in V\left(G), denoted by dv{d}_{v}, is the number of edges incident with vv and the distance between any two vertices u,v∈V(G)u,v\in V\left(G), denoted by duv{d}_{uv}, is ...
Khan Zia Ullah, Hameed Abdul
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
𝕮-inverse of graphs and mixed graphs
Open MathematicsThis article introduces a generalization of the concept of inverse graphs applicable to both graphs and mixed graphs. Given a graph GG with adjacency matrix A(G)A\left(G), the inverse graph G−1{G}^{-1} is defined such that its adjacency matrix is similar
Alomari Omar +2 more
doaj +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Weighted decision making matrix G.
, 2018 Weighted decision making matrix G.
Guoyan Zhao (24853) +2 more
core +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source