Results 121 to 130 of about 1,422,540 (296)

Collective Modes in a Slab of Interacting Nuclear Matter: The effects of finite range interactions

open access: yes, 1993
We consider a slab of nuclear matter and investigate the collective excitations, which develop in the response function of the system. We introduce a finite-range realistic interaction among the nucleons, which reproduces the full G-matrix by a linear ...
A. De Pace   +17 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

On the spectral radius and energy of the degree distance matrix of a connected graph

open access: yesOpen Mathematics
Let GG be a simple connected graph on nn vertices. The degree of a vertex v∈V(G)v\in V\left(G), denoted by dv{d}_{v}, is the number of edges incident with vv and the distance between any two vertices u,v∈V(G)u,v\in V\left(G), denoted by duv{d}_{uv}, is ...
Khan Zia Ullah, Hameed Abdul
doaj   +1 more source

Universal elements of unitriangular matrices groups

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы, 2017
The following theorems are proved for a matrix g from the group of unitriangular matrices over a commutative and associative ring K of finite dimension of greater than three with unity: 1) if the matrix g is universal then all of its elements are on the
A.A. Konyrkhanova, N.G. Khisamiev
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

𝕮-inverse of graphs and mixed graphs

open access: yesOpen Mathematics
This article introduces a generalization of the concept of inverse graphs applicable to both graphs and mixed graphs. Given a graph GG with adjacency matrix A(G)A\left(G), the inverse graph G−1{G}^{-1} is defined such that its adjacency matrix is similar
Alomari Omar   +2 more
doaj   +1 more source

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