Results 251 to 260 of about 634,991 (283)

Capillary Zone Electrophoresis-Mass Spectrometry of Intact G Protein-Coupled Receptors Enables Proteoform Profiling. [PDF]

Anal Chem
Ives AN, Jooß K, Melani RD, Fellers RT, Janetzko J, Kelleher NL.   +5 more
europepmc   +1 more source

G protein-coupled receptors: a gateway to targeting oncogenic EVs? [PDF]

Extracell Vesicles Circ Nucl Acids
Di Niro L, Linders AC, Glynn T, Pegtel DM, Siderius M, Crudden C, Smit MJ.   +6 more
europepmc   +1 more source

Dynamic expression of endometrial adhesion G protein-coupled receptors during the menstrual cycle and early mouse pregnancy: modulation by ovarian stimulation. [PDF]

F S Sci
Kalakota N, Lemenze A, George L, Zhao Q, Wu T, Morelli SS, Babwah AV, Douglas NC.   +7 more
europepmc   +1 more source

De novo design of miniprotein agonists and antagonists targeting G protein-coupled receptors

Muratspahić E, Feldman D, Kim DE, Qu X, Bratovianu A, Rivera-Sánchez P, Dimitri F, Cao J, Cary BP, Belousoff MJ, Keov P, Chen Q, Ren Y, Fine J, Sappington I, Schlichthaerle T, Zhang JZ, Pillai A, Mihaljević L, Bauer M, Torres SV, Motmaen A, Lee GR, Tran L, Wang X, Goreshnik I, Vafeados DK, Svendsen JE, Hosseinzadeh P, Lindegaard N, Brandt M, Waltenspühl Y, Deibler K, Oostdyk L, Cao W, Anantharaman L, Stewart L, Halloran L, Spangler JB, Sexton PM, Roth BL, Krumm BE, Wootten D, Tate CG, Norn C, Baker D.   +45 more
europepmc   +1 more source

Substrate-specific regulation of the mTORC1 pathway by G protein-coupled receptors

Atkinson SJ, Negoita F, Ritchie WV, Thompson K, Sakamoto K, Thompson D, Hislop JN, Hatakeyama R.   +7 more
europepmc   +1 more source

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G protein-coupled receptors

Current Biology, 1992
The diversity of the G protein-coupled receptor superfamily is now being realised with the molecular cloning of DNA encoding many new receptors and receptor subfamilies. The existing pharmacological definitions of receptor subtypes have been extended dramatically with identification of additional subtypes at the molecular level.
T P, Iismaa, J, Shine
openaire   +2 more sources

G-Protein-Coupled Receptors

2008
G-Protein-coupled receptors mediate many of the hypnotic and analgesic actions of the drugs employed in anesthesia. Notably, opioid agonists represent the most successful and efficacious class of analgesic agents employed over the last century. Also, major clinical advances have been made by the study of alpha(2) adrenoceptor agonists, which possess ...
R D, Sanders, D, Brian, M, Maze
openaire   +2 more sources

G-Protein-Coupled Receptor Microarrays

ChemBioChem, 2002
Membrane-bound proteins represent the single most important class of drug targets. Arraying these proteins is difficult because they typically need to be embedded in membranes to maintain their correctly folded conformations. We describe here the fabrication of microarrays consisting of G-protein-coupled receptors (GPCRs)--the single largest family of ...
Ye, Fang, Anthony G, Frutos, Joydeep, Lahiri   +2 more
openaire   +2 more sources

G Protein-Coupled Receptor Pharmacogenetics

2008
Common G protein-coupled receptor (GPCR) gene variants that encode receptor proteins with a distinct sequence may alter drug efficacy without always resulting in a disease phenotype. GPCR genetic loci harbor numerous variants, such as DNA insertions or deletions and single-nucleotide polymorphisms that alter GPCR expression and function, thereby ...
Miles D, Thompson, Katherine A, Siminovitch, David E C, Cole   +2 more
openaire   +2 more sources