Engineering G protein-coupled receptors for stabilization. [PDF]
Protein SciVelloso JPL +3 more
europepmc +1 more source
A Proposed Structure for Transmembrane Segment 7 of G Protein-Coupled Receptors Incorporating an Asn-Pro/Asp-Pro Motif [PDF]
, 1998 Karel Konvička +3 more
openalex +1 more source
The role of circular RNAs in regulating cytokine signaling in cancer
FEBS Open Bio, EarlyView.Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi +4 more
wiley +1 more source
Extracellular ATP increases agonist potency and reduces latency at class B G protein-coupled receptors. [PDF]
Mol PharmacolZhu S +6 more
europepmc +1 more source
A novel gene codes for a putative G protein‐coupled receptor with an abundant expression in brain [PDF]
, 1996 Brian F. O’Dowd +9 more
openalex +1 more source
FEBS Open Bio, EarlyView.In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley +1 more source
A human gene encodes a putative G protein-coupled receptor highly expressed in the central nervous system [PDF]
, 1998 Patrick J. Donohue +5 more
openalex +1 more source
Identifying prognostic targets in metastatic prostate cancer beyond AR
FEBS Open Bio, EarlyView.Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng +13 more
wiley +1 more source
Capillary Zone Electrophoresis-Mass Spectrometry of Intact G Protein-Coupled Receptors Enables Proteoform Profiling. [PDF]
Anal ChemIves AN +5 more
europepmc +1 more source
G‐protein coupled receptor kinases as modulators of G‐protein signalling
, 1999 Moritz Bünemann, Marie Thérèse Hosey
openalex +2 more sources