Results 341 to 350 of about 777,795 (407)

Role of Leucine-Rich Repeat-Containing G-Protein-Coupled Receptors 4-6 (LGR4-6) in the Ovary and Other Female Reproductive Organs: A Literature Review. [PDF]

Cell Transplant
Chang YH, Wu KC, Wang KH, Ding DC.
europepmc   +1 more source

Recent advances in acid sensing by G protein coupled receptors. [PDF]

Pflugers Arch
Glitsch MD.
europepmc   +1 more source

Exploiting Cell-Based Assays to Accelerate Drug Development for G Protein-Coupled Receptors. [PDF]

Int J Mol Sci
Wu Y, Jensen N, Rossner MJ, Wehr MC.
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Functional autoantibodies against G protein-coupled receptors in hepatic and pulmonary hypertensions in human schistosomiasis. [PDF]

Front Immunol
Botoni FA, Lambertucci JR, Santos RAS, Müller J, Talvani A, Wallukat G.   +5 more
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Structural diversity of G protein-coupled receptors and significance for drug discovery

Nature Reviews Drug Discovery, 2008
Malin C Lagerström, Helgi B Schiöth
exaly   +2 more sources

G-protein-coupled receptors and cancer [PDF]

Nature Reviews Cancer, 2007
G-protein-coupled receptors (GPCRs), the largest family of cell-surface molecules involved in signal transmission, have recently emerged as crucial players in tumour growth and metastasis. Malignant cells often hijack the normal physiological functions of GPCRs to survive, proliferate autonomously, evade the immune system, increase their blood supply ...
R. Dorsam, J. Gutkind
semanticscholar   +3 more sources

This is not a G protein-coupled receptor

Trends in Pharmacological Sciences, 1993
On his canvas entitled 'La trahison des Images' ('The Perfidy of Images'), René Magritte painted a tobacco pipe in a very realistic manner and added the words: 'Ceci n'est pas une pipe' ('This is not a pipe'). In similar style, it is of prime importance to state that the first three-dimensional (3D) models of G protein-coupled receptors (GPCRs) that ...
Marcel Hibert, Susanne A. Trumpp-Kallmeyer, Jan Hoflack, Anne T. Bruinvels   +3 more
openaire   +2 more sources

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints.

Molecular Pharmacology, 2003
The superfamily of G-protein-coupled receptors (GPCRs) is very diverse in structure and function and its members are among the most pursued targets for drug development.
R. Fredriksson, M. Lagerström, Lars-Gustav Lundin, H. Schiöth   +3 more
semanticscholar   +1 more source

G-Protein-Coupled Receptors

2008
G-Protein-coupled receptors mediate many of the hypnotic and analgesic actions of the drugs employed in anesthesia. Notably, opioid agonists represent the most successful and efficacious class of analgesic agents employed over the last century. Also, major clinical advances have been made by the study of alpha(2) adrenoceptor agonists, which possess ...
R D, Sanders, D, Brian, M, Maze
openaire   +2 more sources