Results 151 to 160 of about 12,561,590 (387)

Exploring the Interaction of G-quadruplex Binders with a (3 + 1) Hybrid G-quadruplex Forming Sequence within the PARP1 Gene Promoter Region [PDF]

open access: gold, 2022
Stefania Mazzini   +7 more
openalex   +1 more source

G-Quadruplexes (GQU) [PDF]

open access: yesJournal of Nucleic Acids, 2018
Shozeb Haider   +2 more
openaire   +4 more sources

Enhanced Mechanical and Electrochemical Properties of Carbon Nanotube Fibers via Embedded Sucrose‐Derived Porous Carbon for Mechanoelectrochemical Energy Harvesting

open access: yesAdvanced Functional Materials, EarlyView.
Sucrose‐derived porous carbon network (SPINE‐C) is formed within CNT fibers via FCCVD, bridging inter‐bundles of CNTs and increasing surface area through introduced microporosity. As a result, both mechanical and electrochemical properties are simultaneously enhanced, leading to a 2.8‐fold increase in the power density of a mechano‐electrochemical ...
Hocheol Gwac   +9 more
wiley   +1 more source

Bis-indole derivatives with antitumor activity turn out to be specific ligands of human telomeric G-quadruplex

open access: yesFrontiers in Chemistry, 2014
Bis-indolinone derivatives having either 2,6-disubstituted pyridine core (1a and 1b) or 1,10-disubstituted phenanthroline core (2a and 2b), already known to have antitumor activity, have been tested as potential G-quadruplex binders.
Jussara eAmato   +10 more
doaj   +1 more source

Tunable and Recyclable Piezoelectric Biomaterials via Ion‐Directed Guanine‐Quadruplex Assembly

open access: yesAdvanced Functional Materials, EarlyView.
Guanine‐quadruplex (GQ) assemblies, formed via ion‐mediated self‐assembly of amphiphilic guanine derivatives, are introduced as tunable and recyclable piezoelectric biomaterials. Distinct alkali ions induce unique dipole configurations and piezoelectric outputs, with K⁺ yielding the highest performance.
Seungho Lee   +9 more
wiley   +1 more source

Small Molecule Fluorescent Probes for G- Quadruplex Visualization as Potential Cancer Theranostic Agents

open access: yesMolecules, 2019
G-quadruplexes have gained prominence over the past two decades for their role in gene regulation, control of anti-tumour activity and ageing. The physiological relevance and significance of these non-canonical structures in the context of cancer has ...
Pallavi Chilka   +2 more
doaj   +1 more source

Backbone modified TBA analogues endowed with antiproliferative activity [PDF]

open access: yes, 2017
Background: Thrombin binding aptamer (TBA) is endowed with antiproliferative properties but its potential development is counteracted by concomitant anticoagulant activity. Methods: Five oligonucleotides (ODNs) based on TBA sequence (GGTTGGTGTGGTTGG) and
AMATO, TERESA   +8 more
core   +1 more source

G-quadruplex DNA drives genomic instability and represents a targetable molecular abnormality in ATRX-deficient malignant glioma

open access: yesNature Communications, 2018
Mutational inactivation of ATRX (α-thalassemia mental retardation X-linked) represents a defining molecular alteration in large subsets of malignant glioma. Yet the pathogenic consequences of ATRX deficiency remain unclear, as do tractable mechanisms for
Yuxiang Wang   +10 more
semanticscholar   +1 more source

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