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Unlocking G-quadruplex: Effect of unlocked nucleic acid on G-quadruplex stability
Biochimie, 2011G-quadruplexes are common structural motifs in aptamers. UNA or unlocked nucleic acid is the latest nucleic acid modification. We have attempted to evaluate the impact of UNA modification on the structure and stability of G-quadruplex oligonucleotides for application in aptamer design.
Tani, Agarwal +2 more
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A Topological Classification of G-Quadruplex Structures
Nucleosides, Nucleotides & Nucleic Acids, 2007A topological classification of most quadruplex structures is proposed, based on two main characteristics: 1) the relative orientation of the strands and 2) the nature of the loops connecting the strands.
ESPOSITO, VERONICA +5 more
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A hitchhiker's guide to G-quadruplex ligands
Org. Biomol. Chem., 2008Over the past decade, nucleic acid chemists have seen the spectacular emergence of molecules designed to interact efficiently and selectively with a peculiar DNA structure named G-quadruplex. Initially derived from classical DNA intercalators, these G-quadruplex ligands progressively became the focal point of new excitement since they appear to inhibit
Monchaud, David +1 more
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G-Quadruplexes in c-MYC Promoter as Targets for Cancer Therapy
Biomedicines, 2023Maria Eduarda Mendes +2 more
exaly
G-Quadruplexes in RNA Biology: Recent Advances and Future Directions
Trends in Biochemical Sciences, 2021Anne Cammas +2 more
exaly
Reversible Photoswitching of a G‐Quadruplex
Angewandte Chemie, 2009Shinzi, Ogasawara, Mizuo, Maeda
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Thermodynamic Stability of G‐Quadruplexes: Impact of Sequence and Environment
ChemBioChem, 2021Klaus Weisz, Jagannath Jana
exaly
G-Quadruplexes: More Than Just a Kink in Microbial Genomes
Trends in Microbiology, 2019Perumal Vivekanandan
exaly