Results 21 to 30 of about 50,331 (195)
TSH Activates Macrophage Inflammation by G13- and G15-dependent Pathways
Endocrinology, 2021 AbstractThyroid-stimulating hormone (TSH) treatment activates inhibitor of NF-κB/nuclear factor κB (IκB/NFκB) and extracellular signal-regulated kinase (ERK)–P38 in macrophages, but how these pathways are activated, and how they contribute to the proinflammatory effect of TSH on macrophages remain unknown.
Chongbo Yang +6 more
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Oddities of Quantum Colorings [PDF]
, 2016 The main purpose of this work is to collect some interesting facts related to quantum graph coloring. We consider the orthogonality graph of the three-dimensional vectors with entries from the set {-1, 0, 1}. If we ignore the overall sign of the vectors,
Mancinska, Laura, Roberson, David E.
core +2 more sources
G13 Controls Angiogenesis through Regulation of VEGFR-2 Expression [PDF]
Developmental Cell, 2013 At sites of angiogenesis, the expression of the key angiogenesis regulator vascular endothelial growth factor (VEGF) and its main receptor, VEGF receptor 2 (VEGFR-2), are strongly upregulated. Whereas the processes controlling VEGF expression are well described, the mechanisms underlying VEGFR-2 upregulation have remained unclear.
Sivaraj, Kishor Kumar +5 more
openaire +2 more sources
Cells, 2020 KRAS mutations are found in approximately one third of non-small cell lung cancer (NSCLC) patients. In this study, we aim to investigate whether KRAS G12/G13 mutant allele fraction (MAF) in cell-free DNA (cfDNA) can provide meaningful prognostic ...
Kleita Michaelidou +7 more
doaj +1 more source
Insights into divalent cation regulation and G13-coupling of orphan receptor GPR35
Cell Discovery, 2022 Endogenous ions play important roles in the function and pharmacology of G protein-coupled receptors (GPCRs) with limited atomic evidence. In addition, compared with G protein subtypes Gs, Gi/o, and Gq/11, insufficient structural evidence is accessible ...
Jia Duan +12 more
doaj +1 more source
Thrombin Protease-activated Receptor-1 Signals through Gq- and G13-initiated MAPK Cascades Regulating c-Jun Expression to Induce Cell Transformation [PDF]
, 2003 Although the ability of G protein-coupled receptors to stimulate normal and aberrant cell growth has been intensely investigated, the precise nature of the molecular mechanisms underlying their transforming potential are still not fully understood.
Gutkind, J. Silvio +4 more
core +1 more source
Economics and Business Review, 2020 In this paper an extension of the well-known binomial approach to option pricing is presented. The classical question is: What is the price of an option on the risky asset?
Bieta Volker, Broll Udo, Siebe Wilfried
doaj +1 more source
GRB orphan afterglows in present and future radio transient surveys [PDF]
, 2014 Orphan Afterglows (OA) are slow transients produced by Gamma Ray Bursts seen off-axis that become visible on timescales of days/years at optical/NIR and radio frequencies, when the prompt emission at high energies (X and gamma rays) has already ceased ...
Bernardini, M. G. +13 more
core +3 more sources
An Assessment of Wind Farm Construction Efficiency Using the Real Option Method
Folia Oeconomica Stetinensia, 2016 From a developer’s point of view the construction of a wind farm in Poland is an investment project assessed in terms of economic efficiency. This paper discusses the selection of methods to be used for the assessment of such investments: it proposes to ...
Łukaszewski Tomasz, Głoćko Wojciech
doaj +1 more source
Conformational Activation of Radixin by G13 Protein α Subunit [PDF]
Journal of Biological Chemistry, 2000 G(13) protein, one of the heterotrimeric guanine nucleotide-binding proteins (G proteins), regulates diverse and complex cellular responses by transducing signals from the cell surface presumably involving more than one pathway. Yeast two-hybrid screening of a mouse brain cDNA library identified radixin, a member of the ERM family of three closely ...
R, Vaiskunaite +5 more
openaire +2 more sources