Results 1 to 10 of about 522 (82)

Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling. [PDF]

Nat Commun, 2022
Zhu X, Qian Y, Li X, Xu Z, Xia R, Wang N, Liang J, Yin H, Zhang A, Guo C, Wang G, He Y.   +11 more
europepmc   +1 more source

Neonatal Platelets: Lower G_12/13 Expression Contributes to Reduced Secretion of Dense Granules. [PDF]

Cells, 2022
Schlagenhauf A, Bohler S, Kunze M, Strini T, Haidl H, Erlacher M, Zieger B.   +6 more
europepmc   +1 more source

Heterotrimeric G proteins containing Gβ1γ2 subunits exhibit subtype-specific mobility differences in live cells. [PDF]

PLoS One
Kuchynka O, Kovalchuk A, Nußbaumer M, Sviridova E, Fessl T, Bondar A.   +5 more
europepmc   +1 more source

Gα12 signaling regulates transcriptional and phenotypic responses that promote glioblastoma tumor invasion. [PDF]

Sci Rep, 2023
Chaim OM, Miki S, Prager BC, Ma J, Jeong AY, Lara J, Tran NK, Smith JM, Rich JN, Gutkind JS, Miyamoto S, Furnari FB, Brown JH.   +12 more
europepmc   +1 more source

KRAS signaling networks, mutational heterogeneity, and emerging therapeutic strategies for cancer treatment. [PDF]

Biomark Res
Jin S, Zhang Z, Liang F, Yang Y, Lu A, Liang C.   +5 more
europepmc   +1 more source

The role of G protein conformation in receptor-G protein selectivity. [PDF]

Nat Chem Biol, 2023
Jang W, Lu S, Xu X, Wu G, Lambert NA.
europepmc   +1 more source

Activation of G₁₂-type G proteins in pancreatic β cells protects against impaired glucose homeostasis. [PDF]

Sci Adv
Pittala S, Liu L, Haspula D, Cui Y, Fulgenzi G, Inoue A, Wess J.   +6 more
europepmc   +1 more source

A regulatory node involving Gα_q, PLCβ, and RGS proteins modulates platelet reactivity to critical agonists. [PDF]

J Thromb Haemost, 2023
Gupta S, Cooper M, Zhao X, Yarman Y, Thomson H, DeHelian D, Brass LF, Ma P.   +7 more
europepmc   +1 more source

IGF1 Binding to Integrin αvβ3 Induces Direct Gα13 Binding to IGF1R Kinase. [PDF]

Int J Mol Sci
Takada YK, Wu CY, Takada Y.
europepmc   +1 more source

Convergent selective signaling impairment exposes the pathogenicity of latrophilin-3 missense variants linked to inheritable ADHD susceptibility. [PDF]

Mol Psychiatry, 2022
Moreno-Salinas AL, Holleran BJ, Ojeda-Muñiz EY, Correoso-Braña KG, Ribalta-Mena S, Ovando-Zambrano JC, Leduc R, Boucard AA.   +7 more
europepmc   +1 more source