Results 21 to 30 of about 522 (82)

Mechanistic Foundations of KRAS‐Driven Tumor Ecosystems: Integrating Crosstalk among Immune, Metabolic, Microbial, and Stromal Microenvironment

Advanced Science, Volume 12, Issue 30, August 14, 2025.
KRAS mutations dynamically remodel the tumor microenvironment (TME), fostering immunosuppression, metabolic symbiosis, and stromal plasticity. This review dissects how oncogenic KRAS variants sculpt TME networks and explores actionable vulnerabilities. Emerging strategies combining KRAS inhibitors and TME‐editing approaches offer potential to dismantle
Jiayao Ma, Shenao Fu, Jun Tan, Ying Han, Yihong Chen, Xiangying Deng, Hong Shen, Shan Zeng, Yinghui Peng, Changjing Cai   +9 more
wiley   +1 more source

Abstracts

Molecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +2 more sources

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

KRAS-targeted therapies in colorectal cancer: a systematic analysis of mutations, inhibitors, and clinical trials. [PDF]

NPJ Precis Oncol
Navarro-Jiménez M, González B, Mulet N, Hierro C, Alonso S.   +4 more
europepmc   +1 more source

G protein selectivity in group I metabotropic glutamate receptors. [PDF]

Sci Adv
Lu Y, Wen T, Lu X, Zhang G, Meng T, Liu T, Wang X, Shen Y, Yang X.   +8 more
europepmc   +1 more source

Delineation of the GPR15 receptor-mediated Gα protein signalling profile in recombinant mammalian cells. [PDF]

Basic Clin Pharmacol Toxicol, 2022
Deng Y, Moo EV, Almería CVP, Gentry PR, Vedel L, Mathiesen JM, Bräuner-Osborne H.   +6 more
europepmc   +1 more source

G_12/13 signaling in asthma. [PDF]

Respir Res
McDuffie EL, Panettieri RA, Scott CP.
europepmc   +1 more source

GPCRome-wide analysis of G-protein-coupling diversity using a computational biology approach. [PDF]

Nat Commun, 2023
Matic M, Miglionico P, Tatsumi M, Inoue A, Raimondi F.   +4 more
europepmc   +1 more source

Structural insights into the G-protein subtype selectivity revealed by human sphingosine-1-phosphate receptor 3-G_q complexes. [PDF]

Proc Natl Acad Sci U S A
Yamauchi M, Im D, Maeda S, Ikuta T, Toyomoto M, Asada H, Sugita Y, Kishikawa JI, Noda T, Kato T, Inoue A, Iwata S, Hagiwara M.   +12 more
europepmc   +1 more source

G protein selectivity profile of GPR56/ADGRG1 and its effect on downstream effectors. [PDF]

Cell Mol Life Sci
Jallouli R, Moreno-Salinas AL, Laniel A, Holleran B, Avet C, Jacob J, Hoang T, Lavoie C, Carmon KS, Bouvier M, Leduc R.   +10 more
europepmc   +1 more source