Results 31 to 40 of about 517 (97)

A regulatory node involving Gα_q, PLCβ, and RGS proteins modulates platelet reactivity to critical agonists. [PDF]

J Thromb Haemost, 2023
Gupta S, Cooper M, Zhao X, Yarman Y, Thomson H, DeHelian D, Brass LF, Ma P.   +7 more
europepmc   +1 more source

Convergent selective signaling impairment exposes the pathogenicity of latrophilin-3 missense variants linked to inheritable ADHD susceptibility. [PDF]

Mol Psychiatry, 2022
Moreno-Salinas AL, Holleran BJ, Ojeda-Muñiz EY, Correoso-Braña KG, Ribalta-Mena S, Ovando-Zambrano JC, Leduc R, Boucard AA.   +7 more
europepmc   +1 more source

GPCRome-wide analysis of G-protein-coupling diversity using a computational biology approach. [PDF]

Nat Commun, 2023
Matic M, Miglionico P, Tatsumi M, Inoue A, Raimondi F.   +4 more
europepmc   +1 more source

Investigations on the Molecular Mechanisms of EGFR Signal Transactivation in Human Cancer [PDF]

, 2003
Gschwind, A., Gschwind, Andreas, Gschwind, Andreas Franz   +2 more
core  

IGF1 Binding to Integrin αvβ3 Induces Direct Gα13 Binding to IGF1R Kinase. [PDF]

Int J Mol Sci
Takada YK, Wu CY, Takada Y.
europepmc   +1 more source

Delineation of the GPR15 receptor-mediated Gα protein signalling profile in recombinant mammalian cells. [PDF]

Basic Clin Pharmacol Toxicol, 2022
Deng Y, Moo EV, Almería CVP, Gentry PR, Vedel L, Mathiesen JM, Bräuner-Osborne H.   +6 more
europepmc   +1 more source

KRAS-targeted therapies in colorectal cancer: a systematic analysis of mutations, inhibitors, and clinical trials. [PDF]

NPJ Precis Oncol
Navarro-Jiménez M, González B, Mulet N, Hierro C, Alonso S.   +4 more
europepmc   +1 more source

G_12/13 signaling in asthma. [PDF]

Respir Res
McDuffie EL, Panettieri RA, Scott CP.
europepmc   +1 more source

Structural insights into the G-protein subtype selectivity revealed by human sphingosine-1-phosphate receptor 3-G_q complexes. [PDF]

Proc Natl Acad Sci U S A
Yamauchi M, Im D, Maeda S, Ikuta T, Toyomoto M, Asada H, Sugita Y, Kishikawa JI, Noda T, Kato T, Inoue A, Iwata S, Hagiwara M.   +12 more
europepmc   +1 more source

G protein selectivity profile of GPR56/ADGRG1 and its effect on downstream effectors. [PDF]

Cell Mol Life Sci
Jallouli R, Moreno-Salinas AL, Laniel A, Holleran B, Avet C, Jacob J, Hoang T, Lavoie C, Carmon KS, Bouvier M, Leduc R.   +10 more
europepmc   +1 more source