Results 51 to 60 of about 522 (82)

A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state. [PDF]

Nat Commun
Knight KM, Krumm BE, Kapolka NJ, Ludlam WG, Cui M, Mani S, Prytkova I, Obarow EG, Lefevre TJ, Wei W, Ma N, Huang XP, Fay JF, Vaidehi N, Smrcka AV, Slesinger PA, Logothetis DE, Martemyanov KA, Roth BL, Dohlman HG.   +19 more
europepmc   +1 more source

Gα12 and Gα13 proteins are required for transforming growth factor-β-induced myofibroblast differentiation. [PDF]

Biochem J
Reed EB, Sitikov A, Shin KWD, Hamanaka RB, Cetin-Atalay R, Mutlu GM, Mongin AA, Dulin NO.   +7 more
europepmc   +1 more source

GNA13 suppresses proliferation of ER+ breast cancer cells via ERα dependent upregulation of the MYC oncogene. [PDF]

Breast Cancer Res
Subramanyan LV, Rasheed SAK, Wang L, Ghosh S, Ong MSN, Lakshmanan M, Wang M, Casey PJ.   +7 more
europepmc   +1 more source

Homeostatic scaling of dynorphin signaling by a non-canonical opioid receptor. [PDF]

Nat Commun
Li X, Winters ND, Pandey S, Lankford C, Stoveken HM, Smith E, Chang CT, Zucca S, Scampavia L, Spicer T, Martemyanov KA.   +10 more
europepmc   +1 more source

GPCR-Gα13 Involvement in Mitochondrial Function, Oxidative Stress, and Prostate Cancer. [PDF]

Int J Mol Sci
Wu D, Casey PJ.
europepmc   +1 more source

GproteinDb in 2024: new G protein-GPCR couplings, AlphaFold2-multimer models and interface interactions. [PDF]

Nucleic Acids Res
Pándy-Szekeres G, Taracena Herrera LP, Caroli J, Kermani AA, Kulkarni Y, Keserű GM, Gloriam DE.   +6 more
europepmc   +1 more source

G-Alpha Subunit Abundance and Activity Differentially Regulate β-Catenin Signaling. [PDF]

Mol Cell Biol, 2019
Banu A, Liu KJ, Lax AJ, Grigoriadis AE.
europepmc   +1 more source

Structural basis for the ligand recognition and G protein subtype selectivity of kisspeptin receptor. [PDF]

Sci Adv
Wu Z, Chen G, Qiu C, Yan X, Xu L, Jiang S, Xu J, Han R, Shi T, Liu Y, Gao W, Wang Q, Li J, Ye F, Pan X, Zhang Z, Ning P, Zhang B, Chen J, Du Y.   +19 more
europepmc   +1 more source

Synaptic Gα12/13 signaling establishes hippocampal PV inhibitory circuits. [PDF]

Proc Natl Acad Sci U S A
Garbett K, Tosun B, Lopez JM, Smith CM, Honkanen K, Sando RC.   +5 more
europepmc   +1 more source

Structural insights into isoform-specific RAS-PI3Kα interactions and the role of RAS in PI3Kα activation. [PDF]

Nat Commun
Czyzyk D, Yan W, Messing S, Gillette W, Tsuji T, Yamaguchi M, Furuzono S, Turner DM, Esposito D, Nissley DV, McCormick F, Simanshu DK.   +11 more
europepmc   +1 more source