Results 41 to 50 of about 517 (97)

Conformational Signatures of Preassembled and Active Complexes of 5-HT₇ with the G_s Protein. [PDF]

J Chem Inf Model
Zara Z, Nicoli A, He R, Kulik N, Reha D, Bondar A, Di Pizio A.   +6 more
europepmc   +1 more source

Identification of three novel GNAO1 variants in a Chinese cohort with GNAO1 encephalopathy: expanding the clinical and genetic spectrum. [PDF]

Orphanet J Rare Dis
Mei D, Gu Y, Zhang B, Mei S, Wang X, Ma Y, Deng J, Tang J.   +7 more
europepmc   +1 more source

Orphan GPR50 Restrains Neurite Outgrowth and Cell Migration by Activating the G_12/13 Protein-RhoA Pathway in Neural Progenitor Cells and Tanycytes. [PDF]

J Pineal Res
Ahmad R, Luka M, Journe AS, Gallet S, Hegron A, Do Cruzeiro M, Millan MJ, Delagrange P, Masri B, Dam J, Prevot V, Jockers R.   +11 more
europepmc   +1 more source

G_12/13-mediated signaling stimulates hepatic glucose production and has a major impact on whole body glucose homeostasis. [PDF]

Nat Commun
Pittala S, Haspula D, Cui Y, Yang WM, Kim YB, Davis RJ, Wing A, Rotman Y, McGuinness OP, Inoue A, Wess J.   +10 more
europepmc   +1 more source

New insights into RAS in head and neck cancer. [PDF]

Biochim Biophys Acta Rev Cancer, 2023
Jagadeeshan S, Novoplansky OZ, Cohen O, Kurth I, Hess J, Rosenberg AJ, Grandis JR, Elkabets M.   +7 more
europepmc   +1 more source

The M3 Muscarinic Acetylcholine Receptor Can Signal through Multiple G Protein Families. [PDF]

Mol Pharmacol
Smith JS, Hilibrand AS, Skiba MA, Dates AN, Calvillo-Miranda VG, Kruse AC.   +5 more
europepmc   +1 more source

Mediating kinase activity in Ras-mutant cancer: potential for an individualised approach? [PDF]

Front Pharmacol
Healy FM, Turner AL, Marensi V, MacEwan DJ.   +3 more
europepmc   +1 more source

Receptor-independent regulation of Gα13 by alpha-1-antitrypsin C-terminal peptides. [PDF]

J Biol Chem
Park Y, Matsumoto S, Ogata K, Ma B, Kanada R, Isaka Y, Arichi N, Liang X, Maki R, Kozasa T, Okuno Y, Ohno H, Ishihama Y, Toyoshima F.   +13 more
europepmc   +1 more source

Amphetamines signal through intracellular TAAR1 receptors coupled to Gα₁₃ and Gα_S in discrete subcellular domains. [PDF]

Mol Psychiatry, 2021
Underhill SM, Hullihen PD, Chen J, Fenollar-Ferrer C, Rizzo MA, Ingram SL, Amara SG.   +6 more
europepmc   +1 more source

The adhesion GPCR ADGRL2 engages Gα13 to enable epidermal differentiation. [PDF]

Proc Natl Acad Sci U S A
Yang X, He F, Lopez-Pajares V, Porter DF, Garbett K, Siprashvili Z, Ducoli L, Meyers RM, Reynolds DL, Lan Huong Bui D, Hong A, Nguyen DT, Jing Y, Mondal S, Ko L, Tao S, Singal B, Sando R, Skiniotis G, Khavari PA.   +19 more
europepmc   +1 more source