Results 41 to 50 of about 522 (82)

G Protein Selectivity in Dopamine Receptors is Determined before GDP Release. [PDF]

Biochemistry
Tawfeeq C, Hilibrand AS, Smith JS, Portillo J, Kruse AC, Abrol R.   +5 more
europepmc   +1 more source

Targeting KRAS mutations: orchestrating cancer evolution and therapeutic challenges. [PDF]

Signal Transduct Target Ther
Choucair K, Imtiaz H, Uddin MH, Nagasaka M, Al-Hallak MN, Philip PA, El-Rayes B, El-Rayes B, Pasche BC, Azmi AS.   +9 more
europepmc   +1 more source

Stabilization of interdomain closure by a G protein inhibitor. [PDF]

Proc Natl Acad Sci U S A
Todd TD, Vithani N, Singh S, Bowman GR, Blumer KJ, Soranno A.   +5 more
europepmc   +1 more source

Agonist-induced formation of unproductive receptor-G₁₂ complexes. [PDF]

Proc Natl Acad Sci U S A, 2020
Okashah N, Wright SC, Kawakami K, Mathiasen S, Zhou J, Lu S, Javitch JA, Inoue A, Bouvier M, Lambert NA.   +9 more
europepmc   +1 more source

Pancreatic acinar cell signalling and function exhibit an absolute requirement for activation of Gα_q. [PDF]

J Physiol
Takano T, Franchini L, Wagner LE, Cooley M, Groblewski GE, Orlandi C, Yule DI.   +6 more
europepmc   +1 more source

G Protein Activation Occurs via a Largely Universal Mechanism. [PDF]

J Phys Chem B
Vithani N, Todd TD, Singh S, Trent T, Blumer KJ, Bowman GR.   +5 more
europepmc   +1 more source

RESEARCH CHALLENGES IN STAGE III AND IV RAS-ASSOCIATED CANCERS: A Narrative Review of the Complexities and Functions of the Family of <i>RAS</i> Genes and Ras Proteins in Housekeeping and Tumorigenesis. [PDF]

Biology (Basel)
McDonald RA, Varela-Ramirez A, Ashley AK.   +2 more
europepmc   +1 more source

Lysophosphatidic acid-mediated NF-κB activation promotes FOXC2 expression essential for lymphatic valve development. [PDF]

J Clin Invest
Yasuda D, Sato N, Yanagida K, Hashidate-Yoshida T, Shiiya T, Shindou H, Taira A, Ebihara T, Shimizu T, Hirashima M, Mizuno S, Takahashi S, Ishii S.   +12 more
europepmc   +1 more source

A postzygotic GNA13 variant upregulates the RHOA/ROCK pathway and alters melanocyte function in a mosaic skin hypopigmentation syndrome. [PDF]

Nat Commun
El Masri R, Iannuzzo A, Kuentz P, Tacine R, Vincent M, Barbarot S, Morice-Picard F, Boralevi F, Oillarburu N, Mazereeuw-Hautier J, Duffourd Y, Faivre L, Sorlin A, Vabres P, Delon J.   +14 more
europepmc   +1 more source

Identification of Gα₁₂-vs-Gα₁₃-coupling determinants and development of a Gα_12/13-coupled designer GPCR. [PDF]

Sci Rep
Tatsumi M, Cruz C, Kamakura N, Kuwabara R, Nakamura G, Ikuta T, Abrol R, Inoue A.   +7 more
europepmc   +1 more source