Results 41 to 50 of about 44,394 (194)

The Process Approach in the Financial Management of Insurance Firms

Foundations of Management, 2020
The significance of insurance activity is constantly growing, generating new problems and posing new challenges. One of these challenges is meeting the growing requirements and expectations of customers.
Gąsiorkiewicz Lech
doaj   +1 more source

Constructing Calabi-Yau Metrics From Hyperkahler Spaces

, 2010
Recently, a metric construction for the Calabi-Yau 3-folds from a four-dimensional hyperkahler space by adding a complex line bundle was proposed. We extend the construction by adding a U(1) factor to the holomorphic (3,0)-form, and obtain the explicit ...
Lu, H., Pang, Yi, Wang, Zhao-Long
core   +1 more source

Transient Transfection of Rolling‐Circle Amplified DNA in Biomanufacturing‐Relevant Mammalian Cell Lines: A Comparison of Transfection Conditions for Optimal Protein Expression

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Rolling‐circle amplification (RCA) is a completely synthetic and rapid mechanism for scaling‐up bulk DNA that eliminates requirements for large‐scale bacterial fermentation. Several reports have described the surprising ability of large unprocessed (hyperbranched) rolling circle‐amplified DNA (RCA DNA) to effectively transfect cultured cells ...
Evelina Loghin, Erik Kvam, Lisa Lowery, Nathan Hudson, Jenny Keen, Brian Davis, Roger B. Dodd, Christine Surrette, John Nelson   +8 more
wiley   +1 more source

Global fits of the two-loop renormalized Two-Higgs-Doublet model with soft $Z_2$ breaking

, 2015
We determine the next-to-leading order renormalization group equations for the Two-Higgs-Doublet model with a softly broken $Z_2$ symmetry and CP conservation in the scalar potential.
Chowdhury, Debtosh, Eberhardt, Otto
core   +1 more source

Radially truncated galactic discs [PDF]

, 2000
We present the first results of a systematic analysis of radially truncated exponential discs for four galaxies of a complete sample of disc-dominated edge-on spiral galaxies. The discs of our sample galaxies are truncated at similar radii on either side
Abe, Bahcall, Baldwin, Barnaby, Barteldrees, Bottema, Bottema, Bottema, Casertano, de Grijs, de Grijs, de Grijs, de Grijs, de Vaucouleurs, de Vaucouleurs, Freeman, Fry, Giovanelli, Gunn, Hunter, Jensen, Karen H. Wesson, Kent, Knapen, Kylafis, Larson, Lauberts, Lequeux, Mathewson, May, Michiel Kregel, Morrison, Näslund, Persic, Pohlen, Pohlen, Richard de Grijs, Sasaki, Seiden, Seiden, Shaw, Toomre, van der Kruit, van der Kruit, van der Kruit, van der Kruit, van der Kruit, van Dokkum, Xilouris   +48 more
core   +5 more sources

NQO1‐Responsive Prodrug for in Cellulo Release of Cytochalasin B as Cancer Cell‐Targeted Migrastatic

Small, EarlyView.
The design, synthesis, biochemical, and cell biological evaluation of the NQO1‐targeted prodrug BQTML‐CB is reported. BQTML‐CB selectively releases cytochalasin B upon activation by the quinone‐oxidoreductase NQO1 associated with invasiveness of cancer cells, representing a novel approach to improve cancer selectivity and reduce immunosuppressive ...
Mervic D. Kagho, Katharina Schmidt, Christopher Lambert, Lili Jia, Vignesh Venkatakrishnan, Luisa Mehr, Johan Bylund, Klemens Rottner, Marc Stadler, Theresia E. B. Stradal, Philipp Klahn   +10 more
wiley   +1 more source

A generalization of Szebehely's inverse problem of dynamics in dimension three [PDF]

, 2016
Extending a previous paper, we present a generalization in dimension 3 of the traditional Szebehely-type inverse problem. In that traditional setting, the data are curves determined as the intersection of two families of surfaces, and the problem is to ...
Mestdag, T., Prince, G., Sarlet, W.
core   +3 more sources

SARS‐CoV‐2 nucleocapsid protein variants have differential RNA chaperone activity

The FEBS Journal, EarlyView.
The SARS‐CoV‐2 nucleocapsid (N) protein facilitates RNA annealing through its RBD–IDR2–CTD region, identifying it as a functional RNA chaperone. The Omicron BA.5 variant shows reduced chaperone activity compared to the Wuhan wild‐type protein. Although phosphorylation has no effect on wild‐type N, phosphomimetic modification of BA.5 N restores its RNA ...
Sabrina Babl, Julia M. Seidel, Fabian Kugler, Elisabeth Silberhorn, Anna Ludwig, Jonas Abel, Sophia Winklbauer, Niklas Schaub, Silvia Materna‐Reichelt, Kamran Honarnejad, Nataša Stojanović Gužvić, Gernot Längst   +11 more
wiley   +1 more source

Carta Editor Invitado G22

Gremium
El delicado equilibrio entre el patrimonio arquitectónico y urbano con la dinámica turística con la fuerte influencia de la vida homogeneizante posmoderna en nuestras ciudades se ha vuelto un tema central en el panorama profesional y académico contemporáneo.
Alma Pineda Almanza, David Navarrete Escobedo   +1 more
openaire   +1 more source

Compensation for Those Indirectly Affected by the Death of a Household Member

Economics and Culture, 2017
This article demonstrates the size of the budget gap that arises in a household after the death of that member who was the breadwinner of the family. It also describes how this gap can be covered by motor vehicle liability insurance.
Jędrzychowska Anna
doaj   +1 more source