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Residues F16-G33 and A784-N823 within platelet thrombospondin-1 play a major role in binding human neutrophils: Evaluation by two novel binding assays

Journal of Laboratory and Clinical Medicine, 2000
The thrombospondin-1 (TSP1) structural requirements within its heparin-binding domain (HBD)(30 kd) or within the other domains of the molecule (450 kd) that interact with neutrophils (PMNs) have not been delineated. Synthetic peptides based on the HBD, a TSP1 proteolytic fragment lacking the HBD, a large C-terminal domain of TSP1 (210 kd), a TSP1 ...
A, Majluf-Cruz   +8 more
openaire   +2 more sources

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