High frequency of PDGFRA and MUC family gene mutations in diffuse hemispheric glioma, H3 G34-mutant: a glimmer of hope? [PDF]
Journal of Translational Medicine, 2021 Background Diffuse hemispheric glioma H3 G34-mutant (G34-DHG) is a new type of pediatric-type diffuse high-grade glioma in the fifth edition of the WHO Classification of Tumors of the Central Nervous System.
Wanming Hu +4 more
semanticscholar +5 more sources
Analytical and Clinical Performance of a Liquid Chromatography-Tandem Mass Spectrometry Method for Measuring Gastrin Subtypes G34 and G17 in Serum. [PDF]
Clinical Chemistry, 2021 BACKGROUND Two major forms of gastrin, gastrin-17 (G17) and gastrin-34 (G34), exist in blood. However, conventional immunoassay methods can only quantify total gastrin or G17 alone.
Songlin Yu +11 more
semanticscholar +2 more sources
Imaging features associated with H3 K27-altered and H3 G34-mutant gliomas: a narrative systematic review [PDF]
Cancer Imaging, 2022 Background Advances in molecular diagnostics accomplished the discovery of two malignant glioma entities harboring alterations in the H3 histone: diffuse midline glioma, H3 K27-altered and diffuse hemispheric glioma, H3 G34-mutant. Radiogenomics research,
A. Lasocki +3 more
semanticscholar +2 more sources
G34 UK children with progressive neurological disease: differential diagnoses by age [PDF]
British academy of childhood disability and british paediatric neurology association, 2020 Aims To review the cases referred to this UK-wide study of children with progressive intellectual and neurological deterioration (PIND) and analyse the differential diagnoses in these children by age at presentation. Methods Children meeting the case definition for PIND were identified via the British Paediatric Surveillance Unit. Data were obtained
CM Verity +3 more
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Midline invasion predicts poor prognosis in diffuse hemispheric glioma, H3 G34-mutant: an individual participant data review [PDF]
Journal of Neuro-OncologyIntroduction Diffuse hemispheric glioma, H3 G34-mutant (DHGs), is a newly categorized tumor in pediatric-type diffuse high-grade gliomas, World Health Organization grade 4, with a poor prognosis.
Yasuhito Kegoya +12 more
semanticscholar +2 more sources
Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression [PDF]
Proceedings of the National Academy of Sciences, 2020 Significance A high frequency of missense mutations was recently discovered at histone H3.3 glycine 34 in 92% of giant cell tumors of the bone and 17% of high-grade astrocytomas.
Siddhant U. Jain +12 more
semanticscholar +3 more sources
MPC-7 Clinical features of Diffuse hemispheric glioma, H3 G34-mutant in children and young adults [PDF]
American Journal of Surgical Pathology, 2021 The characteristics of H3.3 G34-mutant gliomas in adults have yet to be specifically described. Thirty adults with H3.3 G34-mutant diffuse gliomas were retrospectively reviewed for clinical and pathologic information. Molecular profiling using next-generation sequencing was performed in 29 of the 30 H3.3 G34-mutant patients with 1 patient lacking ...
Y. Takeshima +9 more
openalex +3 more sources
Multiscale Dynamical Scenario of High-mass Star Formation in an IRDC Filament G34 [PDF]
The Astrophysical Journal, 2023 There is growing evidence that high-mass star formation (HMSF) is a multiscale, dynamical process in molecular clouds, where filaments transport gas material between larger and smaller scales.
Si-Rong Pan, Hong-Li Liu, Sheng-li Qin
semanticscholar +4 more sources
MPC-5 Characteristics of H3 G34-mutant gliomas [PDF]
Neuro-Oncology Advances, 2021 Abstract Introduction: Diffuse hemispheric gliomas, H3 G34-mutant (DHG H3G34-mutant) are newly recognized infiltrating gliomas of the cerebral hemispheres of pediatric and young adult patients. We experienced 6 DHG H3G34-mutant cases. In this study, we describe the clinical, radiological and pathological characteristics of these cases.
Yuji Kibe +10 more
openalex +2 more sources
A tRNA-mimic Strategy to Explore the Role of G34 of tRNAGly in Translation and Codon Frameshifting [PDF]
International Journal of Molecular Sciences, 2019 Decoding of the 61 sense codons of the genetic code requires a variable number of tRNAs that establish codon-anticodon interactions. Thanks to the wobble base pairing at the third codon position, less than 61 different tRNA isoacceptors are needed to ...
A. Janvier +5 more
semanticscholar +2 more sources