Results 31 to 40 of about 24,323 (182)

OS5.5 Characteristics of high-grade gliomas with H3 G34 mutation in adults

Japanese Journal of Neurosurgery, 2019
H3 G34-mutant high-grade gliomas occur primarily in children but can also be encountered in adults. The aim of the present study was to describe the characteristics of H3 G34-mutant high-grade gliomas in adults.
T. Picart, M. Barritault, E. Tabouret, A. Idbaih, C. I. Gracia, D. Poncet, J. Honnorat, D. Meyronet, J. Guyotat, F. Ducray   +9 more
semanticscholar   +2 more sources

HGG-08. DIFFUSE HEMISPHERIC GLIOMA, H3 G34-MUTANT: A MULTI-INSTITUTIONAL EXPERIENCE [PDF]

Neuro-Oncology
Abstract BACKGROUND Diffuse hemispheric glioma (DHG), H3 G34-mutant, is a rare, aggressive brain tumor molecularly defined by mutations in the H3-3A gene. Our study explored the association between patient outcomes and key molecular findings, resection extent, and temozolomide (TMZ) use.
Dana Tlais, Jordan T. Roach, Christopher L. Tinkle, Qunyu Zhang, Xiaoyu Li, Lin Tong, Rene McNall‐Knapp, Sarah Rush, Brian H Le, Sara Sinno, Apeksha Agarwal, Kevin Ginn, Richard M. Green, Arzu Onar-Thomas, Asim K. Bag, Jason Chiang   +15 more
openalex   +2 more sources

cIMPACT-NOW update 11: Proposal on adaptation of diagnostic criteria for IDH- and H3-wildtype diffuse high-grade gliomas and for posterior fossa ependymal tumors. [PDF]

Brain Pathol
Abstract The Consortium to Inform Molecular and Practical Approaches to Central Nervous System Tumor Taxonomy (cIMPACT‐NOW) updates provide guidelines for the diagnosis of central nervous system (CNS) tumors and suggestions for future World Health Organization (WHO) classification.
Wesseling P, Capper D, Reifenberger G, Sarkar C, Hawkins C, Perry A, Kleinschmidt-DeMasters B, Komori T, Paulus W, Santosh V, van den Bent M, Weller M, Pfister SM, Tabori U, Figarella-Branger D, Orr BA, Louis DN.   +16 more
europepmc   +2 more sources

Genomic Profiling of Pediatric Solid Tumors With a Dual DNA/RNA Panel: JCCG-TOP2 Study. [PDF]

Cancer Sci
In the JCCG‐TOP2 nationwide pediatric cancer genomic profiling study, 204 patients' tumors and peripheral blood from 50 institutions across Japan were successfully analyzed using a dual DNA/RNA panel. A total of 147 (72%) had potentially actionable findings, including diagnostic, prognostic, and therapeutic findings in 111 (54%), 61 (30%), and 64 (31%),
Tao K, Yoshioka T, Kato M, Komatsu K, Tsujimoto S, Sakamoto K, Tanimura K, Sugiyama M, Sekiguchi M, Nakano Y, Otani Y, Yatabe Y, Yoshida A, Okita H, Hirato J, Kohashi K, Tanaka Y, Kohsaka S, Kubo T, Sunami K, Hirata M, Tsutsumi S, Aburatani H, Koh K, Hirayama M, Karakawa S, Terashita Y, Fujisaki H, Yagi T, Yoneda A, Mochizuki S, Shichino H, Suzuki T, Takimoto T, Ichimura K, Ogawa C, Matsumoto K, Ichikawa H, Kato M.   +38 more
europepmc   +2 more sources

Diffuse Hemispheric Glioma, H3 G34-Mutant With Prominent Perivascular Invasion in a Middle-Aged Man: A Case Report and Literature Review of Middle-Aged and Elderly Cases. [PDF]

Neuropathology
Yuzawa S, Kanemura Y, Hayashi M, Kamikokura Y, Kinoshita M, Tanino M.   +5 more
europepmc   +3 more sources

NIMG-08. IMAGING FINDINGS AND PROGNOSTIC FACTORS IN DIFFUSE HEMISPHERIC GLIOMA, H3 G34-MUTANT [PDF]

Neuro Oncol
Yasuhito Kegoya, Yoshihiro Otani, Ryosuke Ikemachi, Ryo Omae, Sadao Nishigaki, Yohei Inoue, Tsuyoshi Umeda, Madoka Hokama, Ryo Mizuta, Ryoji Imoto, Naoya Kemmotsu, Yasuki Suruga, Shuichiro Hirano, Fumiyo Higaki, Kana Washio, Norio Yamamoto, Shinichiro Koizumi, Kazuhiko Kurozumi, Joji Ishida, Yoshihiro Tanaka, Shota Tanaka   +20 more
europepmc   +3 more sources

Pediatric diffuse hemispheric glioma H3 G34-mutant with gains of the BRAF locus: An illustrative case

Rare Tumors, 2023
Diffuse hemispheric glioma, H3 G34-mutant, is a recently recognized distinct high-grade glioma with a dismal prognosis. In addition to the H3 G34 missense mutation, numerous genetic events have been identified in these malignant tumors, including ATRX ...
Christina F Marlow, J. Cuoco, Austin Hoggarth, Michael S Stump, Lisa S. Apfel, Cara M. Rogers   +5 more
semanticscholar   +1 more source

Some Aspects of Rotation and Magnetic Field Morphology in the Infrared Dark Cloud G34.43+00.24 [PDF]

, 2022
The infrared dark clouds (IRDCs) are molecular clouds with relatively greater values in their magnetic field strengths. For example, the IRDC G34.43+00.24 (G34) has magnetic field strength of the order of a few hundred micro-Gauss.
Hamed Vahdanian, M. Nejad-Asghar
semanticscholar   +1 more source

Pharmacokinetic and pharmacodynamic modelling of the novel human granulocyte colony‐stimulating factor derivative Maxy‐G34 and pegfilgrastim in rats [PDF]

Cell Proliferation, 2009
Markus Scholz, Christoph Engel, D. Apt, S. L. Sankar, E. Goldstein, Markus Loeffler   +5 more
semanticscholar   +2 more sources

Multiple molecular outflows and fragmentation in the IRDC core G34.43+00.24 MM1 [PDF]

Astronomy & Astrophysics, 2021
Context. The fragmentation of a molecular cloud that leads to the formation of high-mass stars occurs on a hierarchy of different spatial scales. The large molecular clouds harbor massive molecular clumps with massive cores embedded in them.
N. Isequilla, M. Ortega, M. B. Areal, S. Paron   +3 more
semanticscholar   +1 more source