Results 61 to 70 of about 7,527 (194)
Mechanisms of Therapeutic Resistance and Recent Advances in Glioblastoma Treatment
Three interconnected processes in glioblastoma (GBM) biology: initiation, stratification, and immunosuppression. 1) Initiation: GBM initiation is proposed to occur through migration of TERT mutation‐bearing neural stem cells from the subventricular zone to the frontal and temporal cortices, where a subsequent oncogenic transformation drives their ...
Emerson Achari +6 more
wiley +1 more source
Bank stability is fundamental for sustaining economic growth, fostering investment, and maintaining confidence in the financial system. In recent years, the rise of Corporate Social Responsibility (CSR) and the creation of CSR committees (CSRCs) have ...
Dhaouadi Hanen +2 more
doaj +1 more source
Kinetic parameter prediction using neural networks identifies limitations to C4 photosynthesis
Schematic overview of the generation of artificial training data and training of neural networks in C4TUNE. Summary Kinetic models of photosynthesis enable time‐resolved predictions of traits related to this key process and provide the means to identify factors limiting photosynthesis.
Philipp Wendering +4 more
wiley +1 more source
G34 Is There a Link Between Attention Deficit Hyperactivity Disorder (ADHD) and Delayed Puberty? [PDF]
Introduction Recently, our department has seen 4 boys with ADHD present with delayed puberty. Only one was on treatment for ADHD with no effect on growth. We conducted a literature search to discover if there was a documented link between ADHD and delayed puberty.
D. I. Kevitiyagala, F. Finlay
openaire +1 more source
Background and PurposeDiffuse hemispheric gliomas, H3 G34‐mutant (DHGs‐G34m), are newly recognized malignant brain tumors characterized by histone gene mutations. However, the neuroradiologic characteristics of these tumors require elucidation.
Yoshiaki Ota +17 more
core +1 more source
M&A motives in the German SME sector: The perception of M&A advisors
Despite their critical role in the European economy, mergers and acquisitions (M&A) involving small- and medium-sized enterprises (SMEs) are less frequently analysed than those involving large corporations. The study’s objective is to address this gap by
Blajer-Gołębiewska Anna +2 more
doaj +1 more source
In an effort to expand the worldwide pool of available medical countermeasures (MCM) against radiation, the PEGylated G-CSF (PEG-G-CSF) molecules Neulasta and Maxy-G34, a novel PEG-G-CSF designed for increased half-life and enhanced activity compared to ...
Sampson, Carol H. +7 more
core +1 more source
Board Structure and Bank Performance: The Mediating Role of Intellectual Capital
Intellectual capital in the knowledge era is a strategic advantage of board structure, which leads to the improvement of a company’s work and the achievement of its goals. The aim of this study is to develop a structural model that connects the corporate
Nikolić Jelena +2 more
doaj +1 more source
Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal +3 more
wiley +1 more source
Immunohistochemistry as a tool for identifying EGFR amplification in CNS tumors
EGFR gene amplification constitutes a diagnostic hallmark for glioblastoma, IDH‐wildtype (GB, IDH‐WT). Herein, we demonstrated that EGFR IHC is a highly specific and sensitive biomarker for identifying EGFR amplification and should be part of the neuropathologist's routine panel of antibodies.
Arnault Tauziède‐Espariat +12 more
wiley +1 more source

