Results 61 to 70 of about 3,837 (207)
Cortisol Recognition by a Conformationally Responsive DNA Aptamer
The full‐length 85mer cortisol aptamer intrinsically populates two metastable conformational states in equilibrium. Cortisol binding redistributes the conformational ensemble by shifting the equilibrium between open and compact states while maintaining the underlying secondary structure. This ligand‐induced tertiary reorganization provides an atomistic
Lakshitha Jasin Arachchige +4 more
wiley +1 more source
Structural water molecules in proteins are notoriously hard to detect in solution. Hyperpolarized water with UV radicals as polarizing agents provides the sensitivity and resolution to detect residue‐specific signatures of structural water with NMR spectroscopy.
Fabian Hecker +3 more
wiley +2 more sources
ABSTRACT Objective Bipolar I Disorder (BP‐I) is frequently misdiagnosed as Major Depressive Disorder (MDD), delaying appropriate treatment. This study aimed to examine treatment patterns among BP‐I patients misdiagnosed with MDD and assess the impact of these regimens on the time until BP‐I diagnosis.
Filmon Haile +2 more
wiley +1 more source
G35 Health care professonals’ knowledge and attitudes towards paediatric pain in one uk hospital [PDF]
Aims This study aimed to ascertain and compare the knowledge and attitudes of health care professionals in one UK hospital relating to paediatric pain. Methods A cross-sectional survey was administered to a convenience sample. The Paediatric Pain Knowledge and Attitudes Questionnaire , a previously validated tool 1 , was administered as an online ...
A Twycross +4 more
openaire +1 more source
ABSTRACT The exclusion of pregnant individuals from clinical trials has resulted in a significant medical knowledge gap for this population. Leveraging real‐world data (RWD) provides a critical window into the prevalence and use of medications during pregnancy.
Jacqueline Williams +4 more
wiley +1 more source
Abstract An unusual chondritic xenolith was found in two sequentially prepared thin sections of a sample from the Krymka (LL3.2) chondrite. The xenolith has a rounded, slightly deformed shape of about 5 mm in apparent diameter and is partially surrounded by a double rim made of an inner fine‐grained silicate‐rich rim and an outer sulfide‐rich rim.
Aelita Girich +6 more
wiley +1 more source
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of Cylactin® as zootechnical additive. The active agent of the additive is Enterococcus lactis NCIMB 10415, and three additive formulations
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +33 more
doaj +1 more source
Genetic Causes of Non-pathogenic Pseudomonas syringae pv. actinidiae Isolates in Kiwifruit Orchards
Bacterial canker disease has become the largest threat to kiwifruit cultivation and production. A monomorphic subpopulation of Pseudomonas syringae pv. actinidiae biovar 3 (Psa3) is responsible for the pandemic worldwide.
Yue Li +8 more
doaj +1 more source
p-Hydroxyacetophenone Amides from Cystobacter ferrugineus, strain Cb G35
A family of six novel p-hydroxyacetophenone amides, 1–6, was isolated from Cystobacter ferrugineus, strain Cb G35. Their structures were elucidated by ESI-TOF mass spectrometry and NMR spectroscopy.
Kathrin I. Mohr (722561) +4 more
core +1 more source
Corporate governance, financial constraints, and dividend policy: Evidence from Pakistan
Information asymmetry between insiders and outsiders creates various issues for a firm, such as the agency problem where managers pursue their own interests even at the cost of the well-being of the firm’s shareholders, and probable external financial ...
M. Azeem +4 more
doaj +1 more source

