Structural and dynamic roles of tandem acyl carrier proteins in aryl polyene biosynthesis in carbapenem-resistant Acinetobacter baumannii. [PDF]
Abstract Aryl polyenes (APEs) are critical secondary metabolites in gram‐negative pathogens, synthesized by polyketide synthases that rely on acyl carrier proteins (ACPs) as essential cofactors. Despite their importance, the structural and functional dynamics of tandem ACPs—ApeE and ApeF—have remained largely uncharacterized.
Lee CY +7 more
europepmc +2 more sources
Chameleonic Nature of Aβ: Implications for Alzheimer's and Other Amyloid Diseases. [PDF]
The energy landscape of Aβ reveals its flexible, “chameleon‐like” behavior, enabling diverse structures from disordered to β‐rich forms. This polymorphism facilitates aggregation, contributing to Alzheimer's disease progression, while the flat landscape also allows disaggregation, potentially slowing disease progression compared to prion proteins with ...
Strodel B.
europepmc +2 more sources
G38(P) Knowledge, attitudes and practice towards epilepsy among primary schools’ teachers in Khartoum locality, Sudan 2016 [PDF]
Objective This study aims to assess primary schools teachers’ knowledge, attitude and practice towards epilepsy. Methods and Materials This is a cross sectional study that was conducted using structured questionnaire; self administered to 202 teachers selected through multistage-clustered sampling technique, in Khartoum locality, Khartoum state ...
Duaa Omer, May Abdelruhman
openaire +1 more source
Does deterioration in rule of law per se create or destroy value?
We investigate the link between the rule of law and equity returns in post-transitional economies over the period January 2010–December 2020 by using panel data regressions.
Byrka-Kita Katarzyna +2 more
doaj +1 more source
Post-Translational Modifications Distinguish Amyloid-β Isoforms in Cerebral Amyloid Angiopathy and Alzheimer's Disease. [PDF]
Cerebral amyloid angiopathy (CAA) is characterized by progressive vascular deposition of fibrillar Aβ. Using Lys‐N digestion and quantitative mass spectrometry, we profiled Aβ isoforms and N‐terminal post‐translational modifications (PTMs) across CAA severities.
Koutarapu S +8 more
europepmc +2 more sources
Tubular initial conditions and ridge formation [PDF]
The 2D azimuth & rapidity structure of the two-particle correlations in relativistic A+A collisions is altered significantly by the presence of sharp inhomogeneities in superdense matter formed in such processes.
Borysov, O. D. +4 more
core +3 more sources
Background and Aims. Grapevine phylloxera, Daktulosphaira vitifoliae (Fitch), feeds on roots and leaves of Vitis spp. Susceptibility to phylloxera differs among rootstocks, such that Vitis spp.
C. W. Clarke +3 more
doaj +1 more source
Italian bank crisis: flexible application of BRRD rules, or a bailout in disguise?
The economic and financial crisis of the year 2008 highlighted the need for banking sector regulation via the creation of the banking union. The Bank Recovery and Resolution Directive (BRRD) represents an important milestone in the formation of the ...
Famfollet Jan, Sankotová Eliška
doaj +1 more source
Corporate Governance of Banks in Poland and Slovenia
This paper focuses on the analysis of the characteristics of corporate governance in banks in Poland and Slovenia between 2005 and 2013. It studies the impact of corporate governance in these banks on their performance.
Pašić Polona +2 more
doaj +1 more source
G38(P) Probiotics for treatment of chronic constipation in children: A Cochrane systematic review [PDF]
Background Chronic constipation is one of the most common paediatric problems seen within primary, secondary and tertiary care. It is hypothesised that the use of probiotics might alter the growth of bacteria in the bowel, promote normal gut physiology and reduce constipation symptoms.
M Gordon +4 more
openaire +1 more source

