Structural and dynamic roles of tandem acyl carrier proteins in aryl polyene biosynthesis in carbapenem-resistant Acinetobacter baumannii. [PDF]
Protein SciAbstract Aryl polyenes (APEs) are critical secondary metabolites in gram‐negative pathogens, synthesized by polyketide synthases that rely on acyl carrier proteins (ACPs) as essential cofactors. Despite their importance, the structural and functional dynamics of tandem ACPs—ApeE and ApeF—have remained largely uncharacterized.
Lee CY +7 more
europepmc +2 more sources
Chameleonic Nature of Aβ: Implications for Alzheimer's and Other Amyloid Diseases. [PDF]
BioessaysThe energy landscape of Aβ reveals its flexible, “chameleon‐like” behavior, enabling diverse structures from disordered to β‐rich forms. This polymorphism facilitates aggregation, contributing to Alzheimer's disease progression, while the flat landscape also allows disaggregation, potentially slowing disease progression compared to prion proteins with ...
Strodel B.
europepmc +2 more sources
EEG–fMRI mapping of asymmetrical delta activity in a patient with refractory epilepsy is concordant with the epileptogenic region determined by intracranial EEG [PDF]
, 2006 We studied a patient with refractory focal epilepsy using continuous EEG-correlated fMRI. Seizures were characterized by head turning to the left and clonic jerking of the left arm, suggesting a right frontal epileptogenic region.
Duncan, J.S. +6 more
core +1 more source
Interplay of 'induced fit' and preorganization in the ligand induced folding of the aptamer domain of the guanine binding riboswitch [PDF]
, 2006 Riboswitches are highly structured elements in the 50-untranslated regions (50-UTRs) of messenger RNA that control gene expression by specifically binding to small metabolite molecules. They consist of an aptamer domain responsible for ligand binding and
Noeske, Jonas +5 more
core +1 more source
Does deterioration in rule of law per se create or destroy value?
International Journal of Management and Economics, 2023 We investigate the link between the rule of law and equity returns in post-transitional economies over the period January 2010–December 2020 by using panel data regressions.
Byrka-Kita Katarzyna +2 more
doaj +1 more source
Australian Journal of Grape and Wine Research, 2023 Background and Aims. Grapevine phylloxera, Daktulosphaira vitifoliae (Fitch), feeds on roots and leaves of Vitis spp. Susceptibility to phylloxera differs among rootstocks, such that Vitis spp.
C. W. Clarke +3 more
doaj +1 more source
Post-Translational Modifications Distinguish Amyloid-β Isoforms in Cerebral Amyloid Angiopathy and Alzheimer's Disease. [PDF]
J NeurochemCerebral amyloid angiopathy (CAA) is characterized by progressive vascular deposition of fibrillar Aβ. Using Lys‐N digestion and quantitative mass spectrometry, we profiled Aβ isoforms and N‐terminal post‐translational modifications (PTMs) across CAA severities.
Koutarapu S +8 more
europepmc +2 more sources
Tubular initial conditions and ridge formation [PDF]
, 2013 The 2D azimuth & rapidity structure of the two-particle correlations in relativistic A+A collisions is altered significantly by the presence of sharp inhomogeneities in superdense matter formed in such processes.
Borysov, O. D. +4 more
core +3 more sources
Italian bank crisis: flexible application of BRRD rules, or a bailout in disguise?
Review of Economic Perspectives, 2020 The economic and financial crisis of the year 2008 highlighted the need for banking sector regulation via the creation of the banking union. The Bank Recovery and Resolution Directive (BRRD) represents an important milestone in the formation of the ...
Famfollet Jan, Sankotová Eliška
doaj +1 more source
Corporate Governance of Banks in Poland and Slovenia
Naše Gospodarstvo, 2016 This paper focuses on the analysis of the characteristics of corporate governance in banks in Poland and Slovenia between 2005 and 2013. It studies the impact of corporate governance in these banks on their performance.
Pašić Polona +2 more
doaj +1 more source