Results 251 to 260 of about 208,134 (332)

Cuproptosis and Disulfidptosis Converge to Empower PD‐L1 Checkpoint Therapy via Cadict‐Induced PD‐L1 Translation

Advanced Science, Volume 13, Issue 25, 4 May 2026.
This study introduces Cadict, an EGFR‐targeted nanodrug that co‐delivers cuproptosis and disulfidptosis inducers to overcome immune resistance. Cadict synergistically enhances tumor cytotoxicity and sensitizes cancers to ICIs by upregulating PD‐L1 via an Eif5b‐dependent translation mechanism, fostering a potent antitumor immune response and ...
Shaoqing Huang, Shiyao Song, Xinhua Zhang, Jialing Gao, Ruihan Pu, Jiatong Dai, Xiaoxue Wu, Lulu Chen, Qinghai Li, Xiaoting Liu, Qi Zhou, Mei Song, Weiling He   +12 more
wiley   +1 more source

Influence of paper mill sludge ash on mechanical, microstructural and durability properties of metakaolin based geocrete. [PDF]

Sci Rep
Yuvaraj K, Arunvivek GK, Kumar P, Sharma KK, Sembeta RY.   +4 more
europepmc   +1 more source

Selinexor and Venetoclax Combination in Patients With Relapsed or Refractory Acute Myeloid Leukemia

American Journal of Hematology, Volume 101, Issue 5, Page 1019-1024, May 2026.
ABSTRACT Preclinical studies showed a synergistic antileukemia activity with combination of selective XPO1 inhibitor selinexor (SEL) and venetoclax (VEN), with potential to overcome VEN resistance by reducing the anti‐apoptotic protein MCL1. In an investigator‐sponsored, open‐label, phase Ib study (NCT03955783), adult patients with relapsed or ...
Somedeb Ball, Farrukh T. Awan, Ben K. Tomlinson, Tess Stopczynski, Melissa A. Fischer, Zhiguo Zhao, Kateryna Fedorov, Ashwin Kishtagari, Sanjay R. Mohan, Gregory D. Ayers, Michael T. Byrne, Michael R. Savona   +11 more
wiley   +1 more source

External validation of a prognostic model predicting renal graft function one year after brain-dead donor kidney transplantation. [PDF]

Langenbecks Arch Surg
Tessmer P, Weigle CA, Meister FA, Wiemann BA, Gwinner W, Mühlfeld A, Kramann R, Kleine-Döpke D, Richter N, Oldhafer F, Vondran FWR, Schrem H, Beetz O, Zwirner U.   +13 more
europepmc   +1 more source

22am2-G5 Effect of Fluid Velocity on Blood Sorting by Using Size-segregation Microfluidic Device

, 2014
Takahiro Suzuki, Tomoki Konishi, Hiromasa Okano, Toshihiro Suzuki, Shinya Ariyasu, Shin Aoki, Ryo Abe, Masanori Hayase   +7 more
openalex   +2 more sources

Four UNH Students Receive Prestigious Fulbright Scholarships [PDF]

, 2010
Wright, Lori
core   +2 more sources

Exploring the Functional Potential of Date (Phoenix dactylifera) Seed Bioactives in Modulating Gut Microbiota in Diabetic Rats

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Date fruits (Phoenix dactilyfera L.) are widely produced with huge wasted by‐products (seeds/pits and fibers) in remarkable nutritional and economic potential value. This study aims to examine the impact of the functional properties of date seeds on health status and gut microbiota (GM) modulation in diabetic rats. Valorization of date seed by‐products
Nouf Abdullah Alharbi, Saleh A. Asanie, Asmahan A. Ali, Aeshah Alhosain, Tarfa Albrahim, Thamer Aljutaily, Huda Aljumayi, Isam A. Mohamed Ahmed, Belal M. Mohammed, Nazeha A. Khalil   +9 more
wiley   +1 more source

Light-Induced Structural Evolutions in Electrostatic Nanoassemblies. [PDF]

Polymers (Basel)
Agarwal M, Schweins R, Gröhn F.
europepmc   +1 more source

A single JAK2‐V617F hematopoietic stem cell can initiate myeloproliferative neoplasm when transplanted into non‐conditioned recipient mice

HemaSphere, Volume 10, Issue 5, May 2026.
Abstract Myeloproliferative neoplasms (MPNs) are clonal disorders of hematopoietic stem cells (HSCs) that are most frequently caused by acquired somatic mutations in JAK2. A number of conditional mouse models of JAK2‐V617F‐driven MPN have been generated that rely on Cre‐LoxP‐mediated activation, resulting in polyclonal disease.
Quentin Kimmerlin, Morgane Hilpert, Nils Hansen, Alexandre Guy, Marc Usart, Jan Stetka, Patryk Sobieralski, Tiago Almeida Fonseca, Hui Hao‐Shen, Radek C. Skoda   +9 more
wiley   +1 more source

90-day oral toxicity study of a salmon nasal cartilage extract containing undenatured collagen and proteoglycan in Sprague-Dawley rats. [PDF]

PLoS One
Takada K, Nakano H.
europepmc   +1 more source