Results 261 to 270 of about 208,134 (332)

[B9, G5] Rencontre Parisienne

Le ciné-œil numérique, 2013
openaire   +2 more sources

Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy

Journal of Biomedical Materials Research Part A, Volume 114, Issue 5, May 2026.
Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy. Created in BioRender. Jain, E. (2026) https://BioRender.com/x4f9o8g. ABSTRACT Osteoarthritis (OA) is a highly prevalent, disabling, and painful disease of the joints, characterized by progressive cartilage degeneration, synovial fibrosis, and pain.
Era Jain, Paul Nana Kwame Sagoe
wiley   +1 more source

Therapeutic targeting of YOD1 disrupts the PAX-FOXO1/N-Myc feedback loop in rhabdomyosarcoma. [PDF]

JCI Insight
Ying W, Yu J, Wang X, Liu J, Deng B, Shao X, Wang J, Tao T, Cao J, He Q, Yang B, Chen Y, Ying M.   +12 more
europepmc   +1 more source

CKDステージG5糖尿病患者5名へのSGLT2阻害薬の投与経験

寺脇 博之, Takafumi Ito, seiji kobayashi, 佳和, 根本, Yasuko Itou, riyuuichi yoshimura, 瞳, 上田, 園田 裕隆, 高野 栄亮, 雄太, 船越, 貴喜, 山内   +10 more
openalex   +1 more source

Differential Trafficking Phenotypes of NPC1 Mutant Proteins Reveal Distinct Cholesterol Accumulation Profiles

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Niemann‐Pick disease type C (NPC) is a rare autosomal recessive lysosomal storage disorder that affects approximately 1 in 100 000 live births. It is primarily caused by mutations in the NPC1 gene, which disrupts intracellular cholesterol transport and leads to lipid accumulation in late endosomes and lysosomes.
Sanaa Abdelmalek Mahmoud, AhmedElmontaser Mergani, Maren von Köckritz‐Blickwede, Hassan Y. Naim   +3 more
wiley   +1 more source

Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy

MedComm, Volume 7, Issue 5, May 2026.
Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley   +1 more source

Autosomal Dominant Tubulointerstitial Kidney Disease Clinical Trial Simulator: Case Reports of Model‐Informed Drug Development

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.
ABSTRACT Autosomal Dominant Tubulointerstitial Kidney Disease (ADTKD) is the third most common inherited monogenic kidney disorder. Mutations in UMOD and MUC1 account for most cases, with the disease characterized by progressive eGFR decline leading to kidney failure. No disease‐modifying therapies exist, and transplantation is the only current option.
Shyam S. Ramesh, Mark Rogge, Jongjin Kim, Sanghoon Kang, Kendrah Kidd, Adrienne Williams, Julie Roignot, Katherine Blakeslee, Anthony J. Bleyer, Sarah Kim   +9 more
wiley   +1 more source

Diversity and distribution of the Trichoptera of Florida, United States, with descriptions of five new species. [PDF]

Zookeys
Rasmussen AK, Denson DR, Orfinger AB, Harris SC.   +3 more
europepmc   +1 more source

G5-6 インドネシア観光資源への選好にみる農村ツーリズムの価値(一般セッション(G5) : 人間科学)(第30回日本行動計量学会大会発表一覧)

, 2004
忍 木谷, 正 長谷部, 希晶 野村
openalex   +1 more source

Detection of Equatorial Plasma Bubbles Using the COSMIC‐2 Rate of TEC Index

Journal of Geophysical Research: Space Physics, Volume 131, Issue 5, May 2026.
Abstract Equatorial plasma bubbles (EPBs) are large‐scale plasma depletion structures that can disrupt Global Navigation Satellite Systems (GNSS) and other space‐based technologies. Several instruments have been employed to study EPB dynamics, with Total Electron Content (TEC) and Rate of TEC change Index (ROTI) data standing out as valuable parameters
Ana L. Christovam, Fabricio S. Prol, Marcio T. A. H. Muella   +2 more
wiley   +1 more source