Results 91 to 100 of about 1,019,197 (220)

Glucose‐6‐phosphate dehydrogenase deficiency as a cause for nonimmune hydrops fetalis and severe fetal anemia: A systematic review

Molecular Genetics & Genomic Medicine
Background Glucose‐6‐phosphate dehydrogenase (G6PD) deficiency is an X‐linked recessive disorder that predisposes individuals to hemolysis due to an inborn error of metabolism.
Neel S. Iyer, Matthew H. Mossayebi, Tracy J. Gao, Lylach Haizler‐Cohen, Daniele Di Mascio, Rodney A. McLaren Jr, Huda B. Al‐Kouatly   +6 more
doaj   +1 more source

An update on glucose-6-phosphate dehydrogenase deficiency in children from Brazzaville, Republic of Congo

Malaria Journal, 2019
Background Malaria transmission-blocking anti-malarial drugs, such as primaquine, offers an effective strategy for reducing the incidence of falciparum malaria.
Nerly Shirère Gampio Gueye, Simon Marie Peko, David Nderu, Felix Koukouikila-Koussounda, Christevy Vouvoungui, Simon Charles Kobawila, Thirumalaisamy P. Velavan, Francine Ntoumi   +7 more
doaj   +1 more source

A combined artificial intelligence–wet lab approach identifies a pivotal role of the NAD+–mitophagy axis on aging and neurodegeneration

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Emerging evidence points to a role of nicotinamide mononucleotide (NAD+) depletion and compromised mitophagy in aging and neurodegenerative diseases. We hypothesize that age‐dependent impairment of the NAD+–mitophagy axis contributes to brain aging and neurodegeneration.
Sofie Lautrup, Shu‐qin Cao, Xi Long, Bonnie Hei Man Liu, Beatriz Escobar‐Doncel, Aristide Ferrante, Johannes Frank, Tomas Schmauck‐Medina, Geoffrey Ho Duen Leung, Kristina Xiao Liang, Ning Lu, Katerina Veverova, Martin Vyhnalek, Frank W. Pun, Alex Zhavoronkov, Evandro Fei Fang   +15 more
wiley   +1 more source

Deep intronic ANK1 variants causing pseudo‐exon inclusion in hereditary spherocytosis: Whole‐genome sequencing and functional assessment

British Journal of Haematology, EarlyView.
Victor Marin, Alexandre Janin, Céline Renoux, Yoann Huguenin, AURAGEN consortium, Stéphanie Dulucq, Louis Lebreton, Philippe Joly, Julian Boutin   +8 more
wiley   +1 more source

The Neuroprotective Potentials of Dual GIP/GLP1‐RA (Tirzepatide): From Preclinical Experiments to Clinical Trials: A Scoping Review

Brain and Behavior, Volume 16, Issue 8, August 2026.
The graphical abstract summarizes the current evidence on the potential neuroprotective effects of tirzepatide (TZP), a dual GIP/GLP‐1 receptor agonist, across mechanistic, preclinical, and clinical domains. Mechanistically, TZP is proposed to exert direct neural effects, preserve mitochondrial function, reduce apoptosis, oxidative stress, and ...
Yousef Hawas, Mohamed Abouzid, Ahmed Farid Gadelmawla, Dalia Kamal Ewis, Abdallah Khatatbeh, Yasmin Negida, Ahmed Negida   +6 more
wiley   +1 more source

Prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency among malaria patients in Upper Myanmar

BMC Infectious Diseases, 2018
BackgroundGlucose-6-phosphate dehydrogenase (G6PD; EC 1.1.1.49) deficiency is one of the most common X-linked recessive hereditary disorders in the world. Primaquine (PQ) has been used for radical cure of P. vivax to prevent relapse. Recently, it is also
Jinyoung Lee, Tae Im Kim, Jung-Mi Kang, Hojong Jun, H. Lê, Thị Lam Thái, W. Sohn, M. Myint, Khin Lin, Tong‐Soo Kim, B. Na   +10 more
semanticscholar   +1 more source

The evolving landscape of the Warburg effect in gastric cancer: From molecular mechanisms to targeted therapy

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
Hypoxia, oncogenic signaling, transcriptional and epigenetic remodeling, and H. pylori–microbiota interactions drive the Warburg effect in gastric cancer. Enhanced glycolysis and lactate export support biosynthesis, remodel the tumor microenvironment, promote stromal activation and immune suppression, and reveal actionable biomarkers and therapeutic ...
Guanmo Liu, Pan Li, Zizhuo Li, Jie Li, Chenggang Zhang, Yihua Wang, Weiming Kang, Xin Ye   +7 more
wiley   +1 more source

Ginseng as a Functional Food Intervention for Interstitial Lung Disease: A Review of the Benefits and Molecular Mechanisms

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
From the perspectives of food science and nutrition, this article reviews the regulatory mechanisms through which ginseng and its major components influence ILD‐related pathological processes and discusses its potential as a functional food and future research directions. ABSTRACT Interstitial lung disease (ILD) encompasses a complex group of disorders
Jiahui Li, Guixin Di, Haijiao Wang, Mengzhu Chen, Keju Wang, Ziyuan Wang, Yanxin Li, Tan Wang   +7 more
wiley   +1 more source

Assessment of Nutritional and Nonnutritional Correlates of Anemia in Pregnancy: A Hospital‐Based Cross‐Sectional Study for Public Health Interventions in the Bono East Region of Ghana

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Anemia in pregnancy (AiP) remains a public health concern in Ghana. The Bono East Region is known for a variety of maternal morbidities, yet the association between inadequate intake of iron‐rich foods and AiP remains underexplored.
Dennis Bardoe, Joana Apenkwa, Daniel Hayford, Ernest Osei, Robert Bagngmen Bio, Salma Bardoe Ahmed   +5 more
wiley   +1 more source

Prevalence of glucose-6-phosphate dehydrogenase deficiency in Cameroonian blood donors

BMC Research Notes, 2019
Objective Deficiency in G6PD is the most common enzymopathy worldwide. It is frequently found in individuals of African descent in whom it can lead to hemolytic crises triggered by the use of certain antimalarial medications and infection. The prevalence
Stephanie M. Lauden, Stella Chongwain, Anzeh Achidi, Ethan Helm, Sarah E. Cusick, Amelia Krug, Tina M. Slusher, Troy C. Lund   +7 more
doaj   +1 more source