Results 111 to 120 of about 1,019,197 (220)

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is associated with elevated mean corpuscular volume (MCV) and bilirubin

BMC Genomic Data
Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common hereditary hemolytic disorder. To provide evidence for the clinical evaluation and management of this disorder, we investigated the differences in erythrocyte and biochemical ...
Zhen Wang, Xiao-Hua Yu, Jian-Lian Liang, Zhi-Xiao Chen, Yu-Chan Huang, Yan-Qing Zeng, Li-Ye Yang   +6 more
doaj   +1 more source

Management of Treatment Resistant EGFR Inhibitor‐Induced Papulopustular Exanthema With Isotretinoin and Dapsone

Australasian Journal of Dermatology, Volume 67, Issue 5, Page 288-293, August 2026.
ABSTRACT Background/Objectives Epidermal growth factor receptor inhibitors (EGFRi) commonly cause papulopustular exanthemas that may compromise the success of cancer therapy. While tetracyclines are first‐line treatment, data on alternative systemic agents for refractory cases remain limited.
Ishana Dixit, Raquel Ruiz Araujo, Pablo Fernandez‐Peñas   +2 more
wiley   +1 more source

Prevalence of G6PD Deficiency in Iran.

International journal of hematology-oncology and stem cell research, 2013
#No Abstract#
Mohammad Shahjahani, Yousef Mortazavi, Bizhan Heli, Ali Dehghanifard   +3 more
openaire   +3 more sources

Development and analytical validation of a targeted short‐read next generation sequencing‐based pharmacogenetic panel for comprehensive variant detection

British Journal of Pharmacology, Volume 183, Issue 16, Page 4735-4760, August 2026.
Abstract Background and Purpose Genomic profiling of patients for genetic variants that modify the effect of specific medications has many benefits, including the possibility of avoiding toxicities and ensuring an adequate effect of the medication. Our intention was to develop a comprehensive, high‐quality pharmacogenetic test panel for clinical use ...
Anna Gréen, Nils Johan Fredriksson, Michael Andresen, Jon Jonasson, Malin Lindqvist Appell, Henrik Gréen   +5 more
wiley   +1 more source

Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease

Cell Proliferation, Volume 59, Issue 8, August 2026.
Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik, Muhammad Dilawar, Junguang Liao, Jie Zheng, Qitao Qian, Ming Xu, Sisi Lin, Xiaobo Zhu, Qiuwei Ge, Limin Jin, Guiqian Chen   +10 more
wiley   +1 more source

Genetic analysis and molecular basis of G6PD deficiency among malaria patients in Thailand: implications for safe use of 8-aminoquinolines

Malaria Journal
Background It was hypothesized that glucose-6-phosphate dehydrogenase (G6PD) deficiency confers a protective effect against malaria infection, however, safety concerns have been raised regarding haemolytic toxicity caused by radical cure with 8 ...
Usa Boonyuen, Beatriz Aira C. Jacob, Jutamas Wongwigkan, Kamonwan Chamchoy, Natsamon Singha-art, Natnicha Pengsuk, Duantida Songdej, Emily R. Adams, Thomas Edwards, Supat Chamnanchanunt, Syazwani Itri Amran, Nurriza Ab Latif, Naveen Eugene Louis, Shamini Chandran   +13 more
doaj   +1 more source

Short‐Course Low‐Dose Primaquine for Radical Cure in G6PD‐Normal Patients in the Pre‐Elimination Context of Nepal

Tropical Medicine &International Health, Volume 31, Issue 8, Page 1028-1034, August 2026.
ABSTRACT Background Plasmodium vivax remains a challenge for malaria elimination in Nepal due to its ability to relapse. Radical cure with primaquine is effective but limited by poor adherence to the standard 14‐day low‐dose regimen. In 2022, the WHO recommended administering the same total dose (3.5 mg/kg) over 7 days to improve adherence.
Prakash Ghimire, Gokarna Dahal, Nabaraj Adhikari, Komal Raj Rijal, Sanjib Adhikari, Megha Raj Banjara, Hellen Mnjala, Grant Lee, Sophie Weston, Angela Rumaseb, Anjana Rai, Benedikt Ley, Mohammad Sharif Hossain, Julie A. Simpson, Megha Rajasekhar, Bipin Adhikari, Ric N. Price, Bibek K. Lal, Kamala Thriemer   +18 more
wiley   +1 more source

G6PD deficiency [PDF]

Blood, 1994
openaire   +2 more sources

Melatonin as a protector against endocrine disruption across tissues: A systematic review

Physiological Reports, Volume 14, Issue 15, August 2026.
Graphical Abstract showing the biological mechanisms by which melatonin protects tissues against endocrine disruption. Abstract Endocrine‐disrupting chemicals (EDCs) are widespread environmental pollutants that interfere with hormonal homeostasis and contribute to multisystem toxicity.
Clenie Isingizwe, Gaudence Ndinganire, Abdullateef Isiaka Alagbonsi   +2 more
wiley   +1 more source

Cholestatic Hepatitis in Young Migrants Exposed to Fuel Vapours: An Emerging Toxicity From the Mediterranean Sea

Acta Paediatrica, Volume 115, Issue 8, Page 1801-1803, August 2026.
Antonio Corsello, Simone Maria Calogero Gramaglia, Giuseppe Gramaglia, Gerlando Verruso, Giusy Ranucci   +4 more
wiley   +1 more source