Results 11 to 20 of about 1,019,197 (220)

New WHO classification of genetic variants causing G6PD deficiency. [PDF]

Bull World Health Organ
divider between class II and class III variants. This variability provided a strong argument to abandon this separation. The panel recommended that class I be retained, as chronic nonspherocytic haemolytic anaemia is a rare chronic condition with well ...
Luzzatto L, Bancone G, Dugué PA, Jiang W, Minucci A, Nannelli C, Pfeffer D, Prchal J, Sirdah M, Sodeinde O, Vulliamy T, Wanachiwanawin W, Cunningham J, Bosman A.   +13 more
europepmc   +2 more sources

Incorporating G6PD genotyping to identify patients with G6PD deficiency

Pharmacogenetics and Genomics, 2021
Glucose-6-phosphate-dehydrogenase (G6PD) deficiency is a common X-linked enzyme disorder associated with hemolytic anemia after exposure to fava beans or certain medications. Activity testing is the gold standard for detecting G6PD deficiency; however, this test is affected by various hematologic parameters.
Sarah A, Morris, Kristine R, Crews, Randall T, Hayden, Clifford M, Takemoto, Wenjian, Yang, Donald K, Baker, Ulrich, Broeckel, Mary V, Relling, Cyrine E, Haidar   +8 more
openaire   +3 more sources

Investigation of glucose-6-phosphate dehydrogenase (G6PD) deficiency prevalence in a Plasmodium vivax-endemic area in the Republic of Korea (ROK)

Malaria Journal, 2020
Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most prevalent inborn disorder. This X-chromosome-linked recessive disease affects more than 400 million people globally, and is associated with haemolytic anaemia after medication ...
Wonsig Lee, Sang-Eun Lee, Min Jun Lee, Kyung Tae Noh   +3 more
doaj   +2 more sources

A trade off between catalytic activity and protein stability determines the clinical manifestations of glucose-6-phosphate dehydrogenase (G6PD) deficiency

International Journal of Biological Macromolecules, 2017
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common polymorphism and enzymopathy in humans, affecting approximately 400 million people worldwide. It is responsible for various clinical manifestations, including favism, hemolytic anemia,
Nicholas White, USA Boonyuen, Mallika Imwong   +2 more
exaly   +2 more sources

Serum microRNAs as new biomarkers for detecting subclinical hemolysis in the nonacute phase of G6PD deficiency [PDF]

Scientific Reports
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most common enzymopathies worldwide. Patients with G6PD deficiency are usually asymptomatic throughout their life but can develop acute hemolysis after exposure to free radicals or certain
Kanyarat Boonpeng, Tatsuki Shibuta, Yoshitaka Hirooka, Kasem Kulkeaw, Duangdao Palasuwan, Tsukuru Umemura   +5 more
doaj   +2 more sources

Scrub Typhus Infection Precipitating Hemolysis in a Patient With G6PD Deficiency: A Case Report [PDF]

Clinical Case Reports
Glucose‐6‐phosphate dehydrogenase (G6PD) deficiency is a well‐known red blood cell enzymopathy and a cause of intravascular hemolysis. This case report presents a child with underlying G6PD deficiency who experienced an acute episode of extensive ...
Ravi Shukla, Mandira Shrestha, Chaitanya Darshan Bhattarai, Kiran Lamichhane, Paras Yadav, Debendra Tamatta   +5 more
doaj   +2 more sources

Point-of-Care Testing for G6PD Deficiency: Opportunities for Screening

International Journal of Neonatal Screening, 2018
Glucose-6-phosphate dehydrogenase (G6PD) deficiency, an X-linked genetic disorder, is associated with increased risk of jaundice and kernicterus at birth.
Sampa Pal, Gonzalo Domingo, Emily Gerth-Guyette   +2 more
exaly   +2 more sources

Molecular Characterization of G6PD Deficiency: Report of Three Novel G6PD Variants

Indian Journal of Hematology and Blood Transfusion, 2019
G6PD deficiency is a monogenic, X-linked genetic defect with a worldwide prevalence of around 400 million people and an overall prevalence of 8.5% in India. Hemolytic anemia is encountered in only a small proportion of patients with G6PD variants and is usually triggered by some exogenous agent.
Arun Kumar, Arunachalam, S, Sumithra, Madhavi, Maddali, N A, Fouzia, Aby, Abraham, Biju, George, Eunice S, Edison   +6 more
openaire   +4 more sources

A Review of the Current Status of G6PD Deficiency Testing to Guide Radical Cure Treatment for Vivax Malaria

Pathogens, 2023
Plasmodium vivax malaria continues to cause a significant burden of disease in the Asia-Pacific, the Horn of Africa, and the Americas. In addition to schizontocidal treatment, the 8-aminoquinoline drugs are crucial for the complete removal of the ...
A. Sadhewa, Sarah A Cassidy-Seyoum, S. Acharya, A. Devine, R. Price, Muthoni Mwaura, K. Thriemer, B. Ley   +7 more
semanticscholar   +1 more source

Glucose-6-phosphate dehydrogenase deficiency screening and gene analysis in blood donors of Guangdong province

Hematology, 2022
Objectives The characteristic of glucose-6-phosphate dehydrogenase (G6PD) deficiency is red blood cell (RBC) destruction in response to oxidative stress.
Hong-Feng Liang, Fen Lin, Jin Lu, Zhi-Xiao Chen, Li-Ye Yang   +4 more
doaj   +1 more source