Results 1 to 10 of about 42,009 (160)

Development and validation of a risk prediction model for hepatorenal syndrome in hepatic failure patients based on glucose-6-phosphate dehydrogenase and hepatic and renal function biochemical parameters [PDF]

Journal of Medical Biochemistry
Background: This study aimed to develop and validate a novel risk prediction model for hepatorenal syndrome (HRS) in hepatic failure (HF) patients by integrating glucose-6-phosphate dehydrogenase (G6PD) activity with conventional hepatic and renal ...
Liu Hao, Lan Yanmei, Zhang Kan, Wang Tingshuai, Mao Dewen, Wang Minggang   +5 more
doaj   +2 more sources

Impaired inflammasome activation and bacterial clearance in G6PD deficiency due to defective NOX/p38 MAPK/AP-1 redox signaling

Redox Biology, 2020
Glucose-6-phosphate dehydrogenase (G6PD) is the rate-limiting enzyme of the pentose phosphate pathway that modulates cellular redox homeostasis via the regeneration of NADPH.
Chih-Ching Wu, Arnold Stern, Shih-Hsiang Chen   +2 more
exaly   +3 more sources

Hemolytic Anemia due to Glucose 6 Phosphate Dehydrogenase Deficiency Triggered by Type 1 Diabetes Mellitus

JCRPE, 2023
Glucose 6 phosphate dehydrogenase (G6PD) is expressed in all tissues and is necessary to maintain oxidant stress capacity of cells. G6PD deficiency is the most common enzymopathy in humans and is among the important causes of hemolytic anemia.
Burçe Orman, Semra Çetinkaya, Nergiz Öner, Meltem Akçaboy, Ali Fettah, Naz Güleray Lafcı, Şenay Savaş Erdeve   +6 more
doaj   +1 more source

Haematology audit of 801 COVID-19 patients' basics and beyond- Prospective observational study

Journal of Family Medicine and Primary Care, 2022
Background and Objective: COVID-19 has become a major health concern since 2020. Its clinical presentation varies from asymptomatic cases to cases with respiratory failure needing ICU management.
Richa Juneja, Rasika Gadkari, Nisha Meshram, Kalaiselvi Selvaraj   +3 more
doaj   +1 more source

Malaria radical cure opportunity assessment in India: Discussing opportunities through stakeholder convening workshop and recommendation for improved access to malaria treatment

Journal of Vector Borne Diseases, 2020
India contributes to over 40% of the global Plasmodium vivax disease burden, and P. vivax contributes to approximately one-third of all malaria in India. Government of India has set goals to eliminate malaria by 2030.
Rajiv Tandon, Evan Spark-DePass, Abhijit Sharma, Emily Gerth-Guyette, Laurence Slutsker, Penny Grewal Daumerie, Gonzalo J Domingo, Panayota Bird, Neha Agarwal   +8 more
doaj   +1 more source

G6PD A- is the major cause of G6PD deficiency among the Siddis of Karnataka, India

Annals of Human Biology, 2020
Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human erythroenzymopathy affecting more than 400 million people worldwide. G6PD deficiency was reported in India more than 50 years ago and the prevalence rate varies from
Rati Devendra, Vinod Gupta, Somashekhar S. Biradar, Pradeep Bhat, Shantharam Hegde, S. L. Hoti, Malay B. Mukherjee, Harsha V. Hegde   +7 more
doaj   +1 more source

Molecular Characterization of Erythrocyte Glucose-6-Phosphate Dehydrogenase Deficiency in Different Ethnic Groups of Blood Donors in Mauritania

Frontiers in Bioscience-Scholar, 2023
Background: Glucose-6-phosphate-dehydrogenase (G6PD) deficiency is the most frequent enzymopathy worldwide; it is a genetic disorder that affects red blood cells and causes hemolysis. Here, we conducted a study on G6PD-deficient subjects in Mauritania to
Mariem Taleb, Meryem Bakour, Aminetou Taleb Brahim, Sidi Mohamed Ghaber, Seyid Abdellahi Ebnou Abdem, Aminetou Mohamed, Badiaa Lyoussi   +6 more
doaj   +1 more source

The in vitro effect of 5-FU and Tamoxifen Chemotherapeutics on penthose phosphate pathway enzymes

Cumhuriyet Science Journal, 2021
The pentose phosphate pathway is the metabolic pathway where NADPH, the reducing force in metabolism, and ribose 5-phosphate, the building block of DNA and RNA, are produced.
Yusuf Temel
doaj   +1 more source

Molecular characterization of G6PD mutations reveals the high frequency of G6PD Aures in the Lao Theung population

Malaria Journal, 2021
Background The prevalence and genotypes of G6PD deficiency vary worldwide, with higher prevalence in malaria endemic areas. The first-time assessment of G6PD deficiency prevalence and molecular characterization of G6PD mutations in the Lao Theung ...
Amkha Sanephonasa, Chalisa Louicharoen Cheepsunthorn, Naly Khaminsou, Onekham Savongsy, Issarang Nuchprayoon, Kamonlak Leecharoenkiat   +5 more
doaj   +1 more source

Combined effects of double mutations on catalytic activity and structural stability contribute to clinical manifestations of glucose-6-phosphate dehydrogenase deficiency

Scientific Reports, 2021
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzymopathy in humans, affecting ~ 500 million worldwide. A detailed study of the structural stability and catalytic activity of G6PD variants is required to understand how different ...
Phonchanan Pakparnich, Sirapapha Sudsumrit, Mallika Imwong, Teeraporn Suteewong, Kamonwan Chamchoy, Danaya Pakotiprapha, Ubolsree Leartsakulpanich, Usa Boonyuen   +7 more
doaj   +1 more source