Results 21 to 30 of about 42,097 (242)
Molecular analysis of three novel G6PD variants: G6PD Pedoplis-Ckaro, G6PD Piotrkow and G6PD Krakow.
Acta Biochimica Polonica, 2007 We present three novel mutations in the G6PD gene and discuss the changes they cause in the 3-dimensional structure of the enzyme: 573C-->G substitution that predicts Phe to Leu at position 191 in the C-terminus of helix alphae, 851T-->C mutation which results in the substitution 284Val--> -->Ala in the beta+alpha domain close to the C ...
Maciag, Monika +8 more
openaire +4 more sources
Tafenoquine and G6PD: A Primer for Clinicians [PDF]
Journal of Travel Medicine, 2019 Tafenoquine, an 8-aminoquinoline, is now indicated for causal prophylaxis against all human malarias and as radical curative (anti-relapse) treatment against Plasmodium vivax and Plasmodium ovale. As with other 8-aminoquinolines, tafenoquine causes hemolysis in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency (hemizygous males and ...
Chu, CS, Freedman, DO
openaire +2 more sources
The enzymopathy of G6PD deficiency in Jordan: a demographic and biochemical analysis
Asian Journal of Medical Sciences, 2018 Background: G6PD deficiency is an inherited X-linked recessive condition leading to insufficient levels of glucose-6-phosphate dehydrogenase, thus causing hemolytic anaemia under certain circumstances.
Ahmed Al-Imam
doaj +1 more source
Eliminating vicine and convicine, the main anti-nutritional factors restricting faba bean usage [PDF]
, 2019 Background Faba bean (Vicia faba L.) seeds are an excellent source of plant-based protein. In spite of the vast nutritional and environmental benefits provided by faba bean cultivation, its use as a food crop has been restricted, primarily due to the ...
Andersen, Stig U. +12 more
core +3 more sources
Biomolecules, 2019 Giardia lambia is a flagellated protozoan parasite that lives in the small intestine and is the causal agent of giardiasis. It has been reported that G. lamblia exhibits glucose-6-phosphate dehydrogenase (G6PD), the first enzyme in the pentose phosphate ...
Laura Morales-Luna +17 more
doaj +1 more source
Dr. Sulaiman Al Habib Medical Journal, 2020 Glucose-6-phosphate Dehydrogenase (G6PD) deficiency is an X-linked disorder that mainly affects red blood cells resulting in its lysis manifesting as hemolytic anemia.
Zair Hassan +3 more
doaj +1 more source
Erciyes Medical Journal, 2020 Glucose-6-phosphate dehydrogenase is an enzyme that protects the erythrocytes against oxidative damage. G6PD deficiency is a common disorder in Gulf Countries that may present with hemolytic anemia and acute renal failure after exposure to oxidative ...
Esra Ermis Turak +9 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Background:Plasmodium vivax remains the malaria species posing a major threat to human health worldwide owing to its relapse mechanism. Currently, the only drugs of choice for radical cure are the 8-aminoquinolines (primaquine and tafenoquine), which are
Sirapapha Sudsumrit +8 more
doaj +1 more source
CRISPR/Cas9-based editing of a sensitive transcriptional regulatory element to achieve cell type-specific knockdown of the NEMO scaffold protein [PDF]
, 2019 The use of alternative promoters for the cell type-specific expression of a given mRNA/protein is a common cell strategy. NEMO is a scaffold protein required for canonical NF-κB signaling.
Babaei, Milad +8 more
core +1 more source
Effect of combined G6PD deficiency and diabetes on protein oxidation and lipid peroxidation
BMC Endocrine Disorders, 2021 Background Oxidative Stress, an imbalance in the pro-oxidant/antioxidant homeostasis, occurs in many physiological and non-physiological processes and several human diseases, including diabetes mellitus (DM) and glucose-6-phosphate dehydrogenase (G6PD ...
Naif S. Karadsheh +3 more
doaj +1 more source