HbA1c underperforms in identifying abnormal glucose tolerance in the presence of G6PD deficiency: Insight from the Africans in America study. [PDF]
PLoS ONEG6PD deficiency (G6PD-D) variants are associated with lower hemoglobin A1c (HbA1c) concentrations, raising concerns about the diagnostic efficacy of HbA1c for abnormal glucose tolerance (Abnl-GT) in Africans, in whom risk of G6PD-D and Abnl-GT is high ...
Amy R Bentley +8 more
doaj +2 more sources
Children, 2023 Glucose-6-phosphate dehydrogenase (G6PD) deficiency and polymorphism in uridine diphosphate glucuronosyl transferase 1A1 (UGT1A1) were associated with significant neonatal hyperbilirubinemia (NHB) and increased risk for kernicterus. However, quantitative
Adel Shalata, Arieh Riskin
exaly +3 more sources
Amplicon-based DNA sequencing to characterize Duffy antigen polymorphisms and analysis of Duffy blood system and glucose-6-phosphate dehydrogenase deficiency in Mauritania. [PDF]
PLoS Neglected Tropical DiseasesBackgroundBoth Duffy blood antigen expression and G6PD deficiency are known to be associated with ethnic origin. Updates in epidemiological data on the prevalence of polymorphisms in these two human genes are key information for guiding national programs
Albin Fontaine +5 more
doaj +2 more sources
Frontiers in Genetics, 2021 Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common inherited enzymatic defect. The purpose of this study was to evaluate the profile of G6PD deficiency and investigate the factors associated with the accuracy of newborn screening
Qiwei Guo, Xudong Wang, Haixia Zhang
exaly +3 more sources
Expanded Clinical Pharmacogenetics Implementation Consortium Guideline for Medication Use in the Context of G6PD Genotype [PDF]
Clinical Pharmacology and Therapeutics, 2023 Teri Klein, Roseann Donnelly
exaly +2 more sources
Glucose-6-phosphate dehydrogenase deficiency and the risk of developing systemic lupus erythematosus [PDF]
Frontiers in MedicineObjectiveTo explore the relationship between glucose-6-phosphate dehydrogenase (G6PD) deficiency and the risk of developing systemic lupus erythematosus (SLE).MethodsA case-control study was conducted including 516 female SLE patients (SLE group) and 491
Xiao-hua Yu +10 more
doaj +2 more sources
Pathogens, 2021 Plasmodium vivax malaria is endemic in Mauritania. Individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency may develop acute hemolytic anemia when exposed to 8-aminoquinoline antimalarial drugs, which are indispensable for a complete cure ...
Oum Kelthoum Mamadou Djigo +9 more
doaj +1 more source
Impact of the method of G6PD deficiency assessment on genetic association studies of malaria susceptibility. [PDF]
PLoS ONE, 2009 BACKGROUND:Clinical association studies have yielded varied results regarding the impact of glucose-6-phosphate dehydrogenase (G6PD) deficiency upon susceptibility to malaria.
Marla K Johnson +4 more
doaj +1 more source
Genotype-Phenotype Correlation of G6PD Mutations among Central Thai Children with G6PD Deficiency
Anemia, 2021 Background. Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common X-linked inherited erythroenzymopathy in Thailand. The clinical and hematological manifestations of G6PD deficiency are variable. Objective.
Boonchai Boonyawat +3 more
doaj +1 more source
Assessment of CareStart G6PD rapid diagnostic test and CareStart G6PD biosensor in Mauritania
Infectious Diseases of Poverty, 2021 Background The elimination of Plasmodium vivax malaria requires 8-aminoquinolines, which are contraindicated in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency due to the risk of acute haemolytic anaemia.
Oum Kelthoum Mamadou Djigo +6 more
doaj +1 more source