Results 41 to 50 of about 42,097 (242)

G6PD Deficiency and Parkinson's Disease: An emerging correlation

Journal of Biochemical and Clinical Genetics
Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency, recognized as the most prevalent enzymopathy globally, limits pentose phosphate pathway (PPP), causing oxidative damage to dopaminergic nigrostriatal (DNS) neurons, has been implicated as a
Komal Uppal, Himani Kaushik, Sunil Kumar Polipalli, Somesh Kumar, Seema Kapoor   +4 more
doaj   +1 more source

Fine mapping of Glucose 6 Phosphate Dehydrogenase (G6PD) deficiency in rural area of South West Odisha using the clinical, hematological and molecular approach

Mediterranean Journal of Hematology and Infectious Diseases, 2020
Introduction: The aim of the study was to enumerate the clinical, hematological and molecular spectrum of G6PD deficiency in malaria endemic regions of south west Odisha.
Ravindra Kumar, MPSS Singh, Soumendu Mahapatra, Sonam Chourasia, Malay Kumar Tripathi, John Oommen, Praveen Kumar Bharti, Rajasubramaniam Shanmugam   +7 more
doaj   +1 more source

Glucose-6-phosphate dehydrogenase (G6PD) mutations and haemoglobinuria syndrome in the Vietnamese population [PDF]

, 2009
BACKGROUND: In Vietnam the blackwater fever syndrome (BWF) has been associated with malaria infection, quinine ingestion and G6PD deficiency. The G6PD variants within the Vietnamese Kinh contributing to the disease risk in this population, and more ...
Charlieu, JP, Chau, TT, Day, N, Dunstan, Sarah, Farrar, JJ, Hien, Tran, Hue, NT   +6 more
core   +4 more sources

RUSH for G6PD! [PDF]

Blood, 2016
![Figure][1] A 21-year-old African American man with HIV infection, well controlled with emtricitabine, rilpivirine, and tenofovir, presented with new onset of jaundice. The night before presenting, he took the sexual enhancement drug called “RUSH.” Initial investigations revealed ...
Uqba Khan, Tarik Hadid
openaire   +2 more sources

Simultaneous detection of G6PD mutations using SNPscan in a multiethnic minority area of Southwestern China

Frontiers in Genetics, 2023
Objectives: Baise, a multiethnic inhabited area of southwestern China, is a historical malaria-endemic area with a high prevalence of G6PD deficiency. However, few studies of G6PD deficiency have been conducted in this region.
Huagui Wei, Chunfang Wang, Weiyi Huang, Liqiao He, Yaqun Liu, Huiying Huang, Wencheng Chen, Yuzhong Zheng, Guidan Xu, Liyun Lin, Wujun Wei, Weizhong Chen, Liying Chen, Junli Wang, Min Lin, Min Lin, Min Lin   +16 more
doaj   +1 more source

Glucose-6-phosphate-dehydrogenase deficiency as a risk factor in proliferative disorder development [PDF]

, 2009
Glucose-6-phosphate dehydrogenase (G6PD) is an important site of metabolic control in the pentose phosphate pathway (PPP) which provides reducing power (NADPH) and pentose phosphates.
Alessandra Pani, Antonella Mandas, Claudia Abete, Claudia Norfo, Enrico Peiretti, Fabrizio Angius, Giacomo Diaz, Maurizio Fossarello, Pierluigi Cocco, Sandra Dessì   +9 more
core   +1 more source

3D‐Printed Piezoionic/Bioelectronic Hydrogel for Electro‐Metabolic Regulation of Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
A 3D‐printed piezoionic GPMx hydrogel enables stable electromechanical signal generation under mechanical loading, exhibiting long‐term durability and low fatigue. As a bioactive patch, it restores endogenous bioelectricity to stimulate osteogenesis via Ca2+ influx and mitochondrial activation, while simultaneously enabling label‐free alkaline ...
Sayan Deb Dutta, Myoung Joon Jeon, Youjin Seol, Ki‐Taek Lim   +3 more
wiley   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

African glucose-6-phosphate dehydrogenase alleles associated with protection from severe malaria in heterozygous females in Tanzania [PDF]

, 2015
X-linked Glucose-6-phosphate dehydrogenase (G6PD) A- deficiency is prevalent in sub-Saharan Africa populations, and has been associated with protection from severe malaria.
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core   +7 more sources

Molecular characterization of G6PD mutations identifies new mutations and a high frequency of intronic variants in Thai females.

PLoS ONE, 2023
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked enzymopathy caused by mutations in the G6PD gene. A medical concern associated with G6PD deficiency is acute hemolytic anemia induced by certain foods, drugs, and infections.
Kamonwan Chamchoy, Sirapapha Sudsumrit, Jutamas Wongwigkan, Songsak Petmitr, Duantida Songdej, Emily R Adams, Thomas Edwards, Ubolsree Leartsakulpanich, Usa Boonyuen   +8 more
doaj   +1 more source