Results 51 to 60 of about 23,913 (202)

Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2006
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Y ZahedPasha, M Ahmad Pour, A ZahedPasha
doaj  

Impaired inflammasome activation and bacterial clearance in G6PD deficiency due to defective NOX/p38 MAPK/AP-1 redox signaling

Redox Biology, 2020
Glucose-6-phosphate dehydrogenase (G6PD) is the rate-limiting enzyme of the pentose phosphate pathway that modulates cellular redox homeostasis via the regeneration of NADPH.
Wei-Chen Yen, Yi-Hsuan Wu, Chih-Ching Wu, Hsin-Ru Lin, Arnold Stern, Shih-Hsiang Chen, Jwu-Ching Shu, Daniel Tsun-Yee Chiu   +7 more
doaj   +1 more source

Maternal Lead Exposure Induces Glandular Alterations in the Salivary Glands of Rat Male Offspring

Environmental Toxicology, EarlyView.
ABSTRACT Lead (Pb) is a widely distributed environmental pollutant that is highly noxious due to its toxicokinetic characteristics. Pb exposure can damage vital organ systems, including the central nervous and stomatognathic systems. As salivary glands play an important role in oral homeostasis, this study aimed to investigate the effects of maternal ...
Rayssa Maitê Farias Nazário, Deiweson Souza‐Monteiro, Walessa Alana Bragança Aragão, Luciana Eiró‐Quirino, Leonardo Oliveira Bittencourt, Raquel Fernanda Gerlach, Antônio Hernandes Chaves‐Neto, Michael Aschner, Rafael Rodrigues Lima   +8 more
wiley   +1 more source

A novel G6PD deleterious variant identified in three families with severe glucose-6-phosphate dehydrogenase deficiency

BMC Medical Genetics, 2020
Background Glucose-6-phosphate dehydrogenase deficiency (D-G6PD) is an X-linked recessive disorder resulted from deleterious variants in the housekeeping gene Glucose-6-phosphate 1-dehydrogenase (G6PD), causing impaired response to oxidizing agents ...
Yongqing Tong, Bei Liu, Hongyun Zheng, Anyu Bao, Zegang Wu, Jian Gu, Bi-Hua Tan, Mary McGrath, Shriya Kane, Chunhua Song, Yan Li   +10 more
doaj   +1 more source

Hydroxyurea (hydroxycarbamide) use in adults with haemoglobin SC disease: A real‐world study in Quebec

British Journal of Haematology, EarlyView.
Summary Haemoglobin SC (HbSC) disease is the second most prevalent form of sickle cell disease, but evidence for hydroxyurea (hydroxycarbamide; HU) to prevent pain episodes was limited until the prospective identification of variables as outcomes for treatment (PIVOT) trial.
Alice Girard, Laurianne Charette, Mélissa Haouchine, Laurence Bozec, Mohamed Zakaria Bachir Bouyadjera, Mariane Poitras, Vincent‐Thierry Taillefer, Chloé Trudeau, Yves Pastore, Nathalie Letarte, Stéphanie Forté   +10 more
wiley   +1 more source

Cytomorphology, osmotic fragility, glucose-6-phosphate dehydrogenase and oxidant/antioxidant status in postparturient haemoglobinuria in dairy cattle and buffaloes

Bulgarian Journal of Veterinary Medicine
The present study was carried out to elucidate the role of blood phosphorus (P), erythrocytic glucose-6-phosphate dehydrogenase (G6PD), glutathione peroxidase (GSH-Px), malonaldehyde (MDA), and nitric oxide (NO) on the integrity of the cell membranes of ...
A. I. Hassanin, M. H. Karam , N.-E. M. Aref   +2 more
doaj   +1 more source

Evaluation of the hematological profile of neonatal jaundice among neonates in Erbil city

Advanced Medical Journal
Background and objectives: Neonatal jaundice is the most commonly encountered medical problem in the first two weeks of life, and a common cause of readmission to the hospitals, this study is designed to investigate different hematological parameters in ...
Arazu Ali Zendin, Nawsherwan Sadiq Mohammad, Rawand Polus Shamoon   +2 more
doaj   +1 more source

DNA damage and synaptic and behavioural disorders in glucose-6-phosphate dehydrogenase-deficient mice

Redox Biology, 2020
Mice deficient in glucose-6-phosphate dehydrogenase (G6PD) cannot replenish the cellular antioxidant glutathione, which detoxifies neurodegenerative reactive oxygen species (ROS).
Margaret M. Loniewska, Anmol Gupta, Shama Bhatia, Isabel MacKay-Clackett, Zhengping Jia, Peter G. Wells   +5 more
doaj   +1 more source

Methaemoglobinaemia: From pathophysiology to contemporary clinical management

British Journal of Haematology, EarlyView.
Summary Methaemoglobin (MetHb) is an oxidised form of haemoglobin (Hb) unable to bind oxygen. Raised levels of MetHb reduce the blood's oxygen‐carrying capacity, causing potentially severe hypoxaemia and possible death. The condition arises from three main pathologies: mutations in globin genes causing Haemoglobin‐M, inherited deficiency of the enzyme ...
Alexander J. Twine, David C. Rees
wiley   +1 more source

G6PD Deficiency

Qatar Medical Journal, 2004
G6PD deficiency is the most common enzyme deficiency disease worldwide, affecting 10% of the world's population. It is an X linked recessive disease therefore it affects males more than females (females are usually carriers of the disease).
A. Al Muzrakchi, A. A. Gehani
openaire   +1 more source