Results 51 to 60 of about 42,097 (242)

Inherited hemolytic disorders with high occurrence of b-thalassemia in Sindhi community of Jabalpur town in Madhya Pradesh, India [PDF]

, 2010
Hereditary hemolytic disorders such as hemoglobin disorders, β-thalassemia syndrome, G6PD deficiency, and ABO and Rhesus blood groups are the most common public health problems in India.
Balgir, RS
core   +1 more source

Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila

Advanced Science, EarlyView.
Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu, Xuedi Zhang, Ying Zhou, Jie Zheng, Angyang Sun, Kailong Zhuang, Weiwei Bao, Guanjun Gao   +7 more
wiley   +1 more source

G6PD activity in whole blood distinguishes the pattern of vascular complications in type 2 diabetes [PDF]

Zagazig Journal of Pharmaceutical Sciences
BACKGROUND: Hyperglycemia in type 2 of diabetes significantly contributes to oxidative load, which in turn promotes the evolution of vascular complications.
Farah Kourdi, Mahassen Al-qubaji, Mohamad Sami Joha   +2 more
doaj   +1 more source

Genotype-Phenotype Correlation of G6PD Mutations among Central Thai Children with G6PD Deficiency

Anemia, 2021
Background. Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common X-linked inherited erythroenzymopathy in Thailand. The clinical and hematological manifestations of G6PD deficiency are variable. Objective.
Boonchai Boonyawat, Tim Phetthong, Nithipun Suksumek, Chanchai Traivaree   +3 more
doaj   +1 more source

Paroxysmal Nocturnal Hemoglobinuria with Glucose-6-Phosphate Dehydrogenase Deficiency: A Case Report and Review of the Literature

Case Reports in Oncology, 2019
In this study, we are describing a female patient with paroxysmal nocturnal hemoglobinuria (PNH) and glucose-6-phosphate dehydrogenase (G6PD) deficiency.
Mahmoud S. Eisa, Shehab F. Mohamed, Firyal Ibrahim, Khalid Shariff, Nagham Sadik, Abdulqadir Nashwan, Mohamed A. Yassin   +6 more
doaj   +1 more source

Prospective evaluation of BDProbeTec strand displacement amplification (SDA) system for diagnosis of tuberculosis in non-respiratory and respiratory samples. [PDF]

, 2004
Nucleic acid amplification techniques (NAATs) have been demonstrated to make significant improvements in the diagnosis of tuberculosis (TB), particularly in the time to diagnosis and the diagnosis of smear-negative TB. The BD ProbeTec strand displacement
Billington, OJ, Gillespie, SH, Gosling, RD, Ling, CL, Lipman, MC, McHugh, TD, Patel, S, Pope, CF   +7 more
core   +2 more sources

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Glucose-6-phosphate dehydrogenase deficiency screening and gene analysis in blood donors of Guangdong province

Hematology, 2022
Objectives The characteristic of glucose-6-phosphate dehydrogenase (G6PD) deficiency is red blood cell (RBC) destruction in response to oxidative stress.
Hong-Feng Liang, Fen Lin, Jin Lu, Zhi-Xiao Chen, Li-Ye Yang   +4 more
doaj   +1 more source

Rapid turnover of T cells in acute infectious mononucleosis.

, 2003
During acute infectious mononucleosis (AIM), large clones of Epstein-Barr virus-specific T lymphocytes are produced. To investigate the dynamics of clonal expansion, we measured cell proliferation during AIM using deuterated glucose to label DNA of ...
Asquith, Becca, Beverley, Peter C, Ghattas, Hala, Griffin, George E, Irvine, Andrew J, Macallan, Derek C, Tough, David F, Wallace, Diana L, Worth, Andrew, Zhang, Yan   +9 more
core   +1 more source

Macrophage Glucose-6-Phosphate Dehydrogenase Stimulates Proinflammatory Responses with Oxidative Stress [PDF]

, 2013
Glucose-6-phosphate dehydrogenase (G6PD) is a key enzyme that regulates cellular redox potential. In this study, we demonstrate that macrophage G6PD plays an important role in the modulation of proinflammatory responses and oxidative stress.
A. H. Choi, Aouadi, Baker, Begriche, Beyaert, C. Kozuka, Cooper, Cosentino, Craig, D. D. Sears, Emre, Fialkow, Forman, Frank, G. Choi, Gaetani, Gao, Guo, Gupte, Guyton, Gwinn, H. Jang, H. Masuzaki, Han, Harrison, Haschemi, Hotamisligil, Hotamisligil, Hothersall, Hui, Ishiyama, Ito, J. B. Kim, J. Park, J.-W. Lee, Kahn, Kamata, Kamata, Kanda, Khaper, Kim, Kyaw, Lambeth, Lee, Leopold, Leopold, Lo, Lumeng, M. Ham, Nishi, Nowak, Olefsky, Park, Park, Roos, Salati, Sanna, Schreck, Sekharam, Shoelson, Suganami, Torres, Tsai, van Bruggen, Wang, Wang, Weisberg, Wilmanski, Yuan, Zechner   +69 more
core   +1 more source