Results 71 to 80 of about 42,097 (242)

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

Equine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka, Bianka Świderska, Ewa Sitkiewicz, Izabela Dąbrowska, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

A novel point mutation in a class IV glucose-6-phosphate dehydrogenase variant (G6PD São Paulo) and polymorphic G6PD variants in São Paulo State, Brazil [PDF]

, 2009
In this study, we used red cell glucose-6-phosphate dehydrogenase (G6PD) activity to screen for G6PD-deficient individuals in 373 unrelated asymptomatic adult men who were working with insecticides (organophosphorus and carbamate) in dengue prevention ...
OLIVEIRA, Raimundo Antonio G., OSHIRO, Marilena, HIRATA, Mario H., HIRATA, Rosario D.C., RIBEIRO, Georgina S., MEDEIROS, Tereza M.D., BARRETTO, Orlando C. de O.   +6 more
core   +2 more sources

G6PD DEFICIENCY

The Professional Medical Journal, 2015
Context: Hyperbilirubinemia due to glucose 6 phosphate dehydrogenase(G6PD) deficiency can cause permanent neurological damage and death in neonates.Screening for the enzyme enables timely diagnosis and treatment in cases of G6PD relatedkernicterus. Knowledge of patient G6PD status is also important in treatment of malaria, adisease endemic in Pakistan.
Zahra Rashid Khan, Shumaila Najeeb, Alina Amjad   +2 more
openaire   +2 more sources

Andrographolide Modulates Fibrogenic and Oxidative Stress Responses in Human Lung Fibroblasts

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pulmonary fibrosis is a progressive lung disorder characterized by fibroblast activation and excessive extracellular matrix deposition. Andrographolide (ANDRO) has been reported to attenuate pulmonary fibrosis, but the underlying molecular mechanisms remain incompletely understood.
Yu‐Hsin Tseng, Yen‐Hsien Wu, Yi‐Ching Liu, I‐Chen Chen, Chung‐Yu Yeh, Shang‐En Huang, Ren‐Long Jan, Jwu‐Lai Yeh, Jong‐Hau Hsu   +8 more
wiley   +1 more source

Cytomorphology, osmotic fragility, glucose-6-phosphate dehydrogenase and oxidant/antioxidant status in postparturient haemoglobinuria in dairy cattle and buffaloes

Bulgarian Journal of Veterinary Medicine
The present study was carried out to elucidate the role of blood phosphorus (P), erythrocytic glucose-6-phosphate dehydrogenase (G6PD), glutathione peroxidase (GSH-Px), malonaldehyde (MDA), and nitric oxide (NO) on the integrity of the cell membranes of ...
A. I. Hassanin, M. H. Karam , N.-E. M. Aref   +2 more
doaj   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Cross Sectional Study of Prenatal Diagnosis Uptake Among Individuals With Genetic Conditions

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Prenatal diagnostic genetic testing allows for early identification of significant fetal conditions and enables informed decision‐making regarding management options. The aim of this study was to assess prenatal testing practice among individuals with genetic conditions.
Ebunoluwa Ojo, Roni Zemet, Allyson Nevins, Katherine Abraham, April D. Adams   +4 more
wiley   +1 more source

The Frequency of PON1 L55M Polymorphism and Measurement of Oxidative Stress Parameters (Superoxide Dismutase, Catalase, Thiol, and Carbonyl) in Neonates with G6PD Deficiency Compared to the Control Group

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2019
Introduction: Glucose-6-phosphate dehydrogenase deficiency is the most common enzyme disorder. This enzyme involved in maintaining the balance of active oxygen species and its defect causes oxidative damage. PON1 is an HDL-based glycosylated protein that
Vahide Jamshidi, Vahid Pourshafiei, Mahmoud Vakili, Ali Moradi   +3 more
doaj  

Prevalence of glucose-6-phosphate dehydrogenase deficiency and its association with Plasmodium falciparum infection among children in Iganga distric in Uganda [PDF]

, 2014
BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) is a metabolic enzyme involved in the pentose phosphate pathway, its especially important in red blood cell metabolism.
Denis Bwayo, Fred Kironde, Henry Ddungu, Mark Kaddumukasa   +3 more
core   +1 more source

Proteomic Profiling of Primary Hippocampal Neurons Reveals Noncanonical GFAP Expression and Metabolic Adaptations in Glia‐Free Culture

PROTEOMICS, EarlyView.
ABSTRACT Despite their widespread use as a research model, a comprehensive, quantitative proteomic profile of the cultured hippocampal neurons has remained unexplored. Here, we provide the first global proteomic characterization of primary murine hippocampal neurons cultured for 14 days under near‐physiological glucose conditions (2.5 mM).
Dominika Drulis‐Fajdasz, Kinga Gostomska‐Pampuch, Natalia Pudełko‐Malik, Mariusz Fleszar, Agnieszka Gizak, Jacek R. Wiśniewski, Dariusz Rakus   +6 more
wiley   +1 more source