Results 81 to 90 of about 23,913 (202)

Identification and Validation of Metabolic Hub Genes Using WGCNA and Prognostic Risk Modeling in Acute Myeloid Leukemia

Cancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Acute myeloid leukemia (AML) is an aggressive and molecularly heterogeneous hematologic malignancy associated with poor clinical outcomes, particularly in elderly and high‐risk patients. Increasing evidence suggests that metabolic reprogramming plays a critical role in leukemia progression, immune dysregulation, and therapeutic ...
Samaneh Ramezani, Fatemeh Akhoundi, Reza Valadan, Hossein Asgarian‐Omran   +3 more
wiley   +1 more source

The evolving landscape of the Warburg effect in gastric cancer: From molecular mechanisms to targeted therapy

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
Hypoxia, oncogenic signaling, transcriptional and epigenetic remodeling, and H. pylori–microbiota interactions drive the Warburg effect in gastric cancer. Enhanced glycolysis and lactate export support biosynthesis, remodel the tumor microenvironment, promote stromal activation and immune suppression, and reveal actionable biomarkers and therapeutic ...
Guanmo Liu, Pan Li, Zizhuo Li, Jie Li, Chenggang Zhang, Yihua Wang, Weiming Kang, Xin Ye   +7 more
wiley   +1 more source

G6PD deficiency and malaria selection [PDF]

Heredity, 2011
In his valuable review on genetics of malaria resistance, Hedrick (2011) tackles the interesting issue of the protection against Plasmodium falciparum afforded by G6PD deficiency. Specifically, he quotes data from a study (Ruwende et al., 1995) conducted in Gambia and in Kenya, from which it was claimed that the degree of protection was similar in ...
openaire   +2 more sources

Ginseng as a Functional Food Intervention for Interstitial Lung Disease: A Review of the Benefits and Molecular Mechanisms

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
From the perspectives of food science and nutrition, this article reviews the regulatory mechanisms through which ginseng and its major components influence ILD‐related pathological processes and discusses its potential as a functional food and future research directions. ABSTRACT Interstitial lung disease (ILD) encompasses a complex group of disorders
Jiahui Li, Guixin Di, Haijiao Wang, Mengzhu Chen, Keju Wang, Ziyuan Wang, Yanxin Li, Tan Wang   +7 more
wiley   +1 more source

Prevalence of G6PD deficiency among primary school students in Amol

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2005
Background and Objective: G6PD (Glucose-6-phosphate dehydrogenase) deficiency is the most common enzyme deficiency in human beings. Using fava beans, some drugs are oxidant agents cause life-threatening hemolysis in children and other ages.
A Hashemi, Y ZahedPasha, M Haji Ahmadi, B Alaei   +3 more
doaj  

Assessment of Nutritional and Nonnutritional Correlates of Anemia in Pregnancy: A Hospital‐Based Cross‐Sectional Study for Public Health Interventions in the Bono East Region of Ghana

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Anemia in pregnancy (AiP) remains a public health concern in Ghana. The Bono East Region is known for a variety of maternal morbidities, yet the association between inadequate intake of iron‐rich foods and AiP remains underexplored.
Dennis Bardoe, Joana Apenkwa, Daniel Hayford, Ernest Osei, Robert Bagngmen Bio, Salma Bardoe Ahmed   +5 more
wiley   +1 more source

Metabolic Regulation of Macrophages in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang, Yu Zhang, Jiali Min, Jiahui Yang, Yuchen Li, Hao Zhang, Shanshan Liu   +6 more
wiley   +1 more source

Type 2 Diabetes Mellitus: Molecular Pathogenesis and Therapeutic Interventions

MedComm, Volume 7, Issue 8, August 2026.
This graphical summary illustrates the multiorgan therapeutic landscape for Type 2 diabetes mellitus (T2D), integrating molecular pathogenesis with modern treatment strategies. It depicts how current interventions, including SGLT2 inhibitors, GLP‐1 receptor agonists, and insulin secretagogues, target key organs—kidney, pancreas, gastrointestinal tract,
Shinuan Fei, Xiyue Xiong, Lu Zhang, Jian Zhang, Lawrence W. C. Chan, Hong Jiang, Qingqing Xiong, Changtao Hu, Jie Chen, Sijun Yang   +9 more
wiley   +1 more source

Characterization of G6PD genotypes in G6PD deficiency patients from Suratthani Hospital, Thailand

Journal of Associated Medical Sciences, 2018
Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is highly prevalent in Southeast Asia especially in the area of malaria endemic regions. Primaquine is used for the radical treatment of malaria.
Suwannee Jitueakul, Hansuk Buncherd, Pongsakorn Thawornpan, Aung Win Tung, Supinya Thanapongpichat   +4 more
doaj  

Nucleotide Metabolism in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao, Yiyu Zeng, Yike Xu, Shu Rao, Mouna Khouchani, Hassna Soummane, Jingyi Li, Rui Liu   +7 more
wiley   +1 more source