Results 91 to 100 of about 42,097 (242)

Prevalence of and mothers’ knowledge, attitude and practice towards glucose-6-phosphate dehydrogenase deficiency among neonates with jaundice: a cross-sectional study

BMJ Open, 2020
BackgroundNeonatal jaundice (NNJ) is a frequent complication of glucose-6-phosphate dehydrogenase (G6PD) deficiency.ObjectivesTo estimate the prevalence of G6PD deficiency among neonates with jaundice and to assess mothers’ perception towards G6PD and ...
Zeinab A Kasemy, Wael A Bahbah, Sally M El Hefnawy, Safa H Alkalash   +3 more
doaj   +1 more source

Evaluation of glucose-6-phosphate dehydrogenase stability in stored blood samples [PDF]

, 2016
Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency is the commonest cause of neonatal jaundice in Malaysia. Recently, OSMMR2000-D G6PD Assay Kit has been introduced to quantitate the level of G6PD activity in newborns delivered in Universiti Kebangsaan ...
Alauddin, Hafiza, Azma, Raja Zahratul, Baya, Siti Noor, Ithnin, Azlin, Jalil, Norunaluwar, Mohamed, Emida, Othman, Ainoon   +6 more
core   +1 more source

Development and analytical validation of a targeted short‐read next generation sequencing‐based pharmacogenetic panel for comprehensive variant detection

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Genomic profiling of patients for genetic variants that modify the effect of specific medications has many benefits, including the possibility of avoiding toxicities and ensuring an adequate effect of the medication. Our intention was to develop a comprehensive, high‐quality pharmacogenetic test panel for clinical use ...
Anna Gréen, Nils Johan Fredriksson, Michael Andresen, Jon Jonasson, Malin Lindqvist Appell, Henrik Gréen   +5 more
wiley   +1 more source

A reiterative method for calculating the early bactericidal activity of antituberculosis drugs.

, 2002
Studies of early bactericidal activity (EBA) are important in the rapid evaluation of new antituberculosis drugs. Historically, these have concentrated on the log fall in the viable count in sputum during the first 48 hours of therapy.
Charalambous, Bambos M, Gillespie, Stephen H, Gosling, Roland D   +2 more
core   +1 more source

European S2k guidelines on management of autoimmune blistering diseases in children and adolescents

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Autoimmune blistering disorders (AIBDs) in children are rare, challenging to diagnose and treat and often require immunosuppressants. Until now, no paediatric care guidelines existed. The EADV Task Force for AIBDs has developed the consensus‐based recommendations, enabling physicians to adopt a uniform, tailored treatment strategy to improve outcomes ...
A. Nanda, B. Tedbirt, C. Bodemer, M. C. Bolling, M. El Hachem, M. Nikolić, E. Benton, M. Caproni, D. De, D. Didona, K. Drenovska, M. Goebeler, M. Hertl, B. Horváth, M. Kasperkiewicz, D. Kiritsi, M. Larralde, A. V. Marzano, J. Meijer, D. F. Murrell, J. Powell, E. Sprecher, N. S. Chandran, M. M. Tomayko, S. Uzun, N. van Beek, H. Ott, A. Patsatsi, A. Torrelo, A. Welfringer‐Morin, E. Schmidt, P. Joly   +31 more
wiley   +1 more source

Nine Different Glucose-6-phosphate Dehydrogenase (G6PD) Variants in a Malaysian Population with Malay, Chinese, Indian and Orang Asli (Aboriginal Malaysian) Backgrounds [PDF]

, 2008
The Malaysian people consist of several ethnic groups including the Malay, the Chinese, the Indian and the Orang Asli (aboriginal Malaysians). We collected blood samples from outpatients of 2 hospitals in the State of Selangor and identified 27 glucose-6-
Abdul Manand, Encik Abdul Salim, Arai, Meiji, Hidayah, Noor Ishak, Hirai, Makoto, Isa, Zaleha Mohamed, Luo, Enjie, Matsuoka, Hiroyuki, Wang, Jichun   +7 more
core   +1 more source

Short‐Course Low‐Dose Primaquine for Radical Cure in G6PD‐Normal Patients in the Pre‐Elimination Context of Nepal

Tropical Medicine &International Health, EarlyView.
ABSTRACT Background Plasmodium vivax remains a challenge for malaria elimination in Nepal due to its ability to relapse. Radical cure with primaquine is effective but limited by poor adherence to the standard 14‐day low‐dose regimen. In 2022, the WHO recommended administering the same total dose (3.5 mg/kg) over 7 days to improve adherence.
Prakash Ghimire, Gokarna Dahal, Nabaraj Adhikari, Komal Raj Rijal, Sanjib Adhikari, Megha Raj Banjara, Hellen Mnjala, Grant Lee, Sophie Weston, Angela Rumaseb, Anjana Rai, Benedikt Ley, Mohammad Sharif Hossain, Julie A. Simpson, Megha Rajasekhar, Bipin Adhikari, Ric N. Price, Bibek K. Lal, Kamala Thriemer   +18 more
wiley   +1 more source

Deficiência de glicose-6-fosfato desidrogenase eritrocitária em recém-nascidos do sexo masculino e sua relação com a icterícia neonatal [PDF]

, 2010
Glucose-6-phosphate dehydrogenase (G6PD) deficiency, the commonest red cell enzymopathy in humans, has an X-linked inheritance. The major clinical manifestations are drug induced hemolytic anemia, neonatal jaundice and chronic nonspherocytic hemolytic ...
AMORIM, Maria do Socorro T., BARRETTO, Orlando C. O., IGLESSIAS, Marli Auxiliadora C., MEDEIROS, Tereza Maria D., MOREIRA, Susiane S., SANTOS, Rosa Maria V., SILVA, Rosângela T.   +6 more
core   +1 more source

Molecular Characterization of G6PD Deficiency: Report of Three Novel G6PD Variants

Indian Journal of Hematology and Blood Transfusion, 2019
G6PD deficiency is a monogenic, X-linked genetic defect with a worldwide prevalence of around 400 million people and an overall prevalence of 8.5% in India. Hemolytic anemia is encountered in only a small proportion of patients with G6PD variants and is usually triggered by some exogenous agent.
Arun Kumar, Arunachalam, S, Sumithra, Madhavi, Maddali, N A, Fouzia, Aby, Abraham, Biju, George, Eunice S, Edison   +6 more
openaire   +3 more sources

Depigmentation Outcomes in Pigmented Oral Lichen Planus Managed With Mycophenolate Mofetil

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Pigmented oral lichen planus (OLP) is a chronic, immune‐mediated mucosal disorder associated with dark black or brown discoloration secondary to the excess melanin deposition. This medical condition is often accompanied by the typical white (reticular) or red (erosive) OLP features and is refractory to conventional therapy. We report a case of
Tania Biswas, Atul Anand Bajoria, Noureen Nahar, Pallawi Sinha, Jitendra Sharan, Smriti K. C. Basynat   +5 more
wiley   +1 more source