Results 111 to 120 of about 42,097 (242)
To combat BET inhibitor resistance in triple‐negative breast cancer, we developed two single‐cell computational frameworks. FR20 quantifies resistance by integrating ferroptosis‐related gene signatures, while D‐FR20 screens for potential re‐sensitizers.
Haizhou Liu +6 more
wiley +1 more source
The First Case of Linear Cutaneous Lupus Erythematosus Following Covid‐19 Vaccination: A Case Report
Clinical manifestation of LCDLE characterized by lesions following a progressive distal pattern along the lateral arm, forearm, and dorsal hand. ABSTRACT Linear cutaneous discoid lupus erythematosus (LCDLE) is a rare presentation of lupus erythematosus, more frequently observed in children and young adults.
Fatemeh Saberi +5 more
wiley +1 more source
COMPUTATIONAL ANALYSIS OF DIMER G6PD STRUCTURE TO ELUCIDATE PATHOGENICITY OF G6PD VARIANTS
An inherent genetic enzyme disorder in humans, known as glucose-6-phosphate dehydrogenase (G6PD) deficiency, arises due to specific mutations. While the prevailing approach for investigating G6PD variants involves biochemical analysis, the intricate structural details remain limited, impeding a comprehensive understanding of how different G6PD variants
Chandran, Shamini +5 more
openaire +2 more sources
Metabolic Reprogramming Analysis of Wheat Response to Low Temperature Stress Under Nitrogen Supply
Low temperature stress triggers a defense network that maintains growth at the expense of inhibiting photosynthesis and chlorophyll synthesis. Temperature recovery effectively repairs low temperature‐induced damage and enhances stress resistance, while nitrogen supply can further augment these protective processes to strengthen cold tolerance ...
Qiujuan Jiao +9 more
wiley +1 more source
Background and Objective: Glutathione as a master antioxidant plays a key role in eliminating free radicals from your body and in preserving cell membrane integrity esp. blood cells.
H Rafeemehr
doaj
G6PD deficiency and malaria selection [PDF]
In his valuable review on genetics of malaria resistance, Hedrick (2011) tackles the interesting issue of the protection against Plasmodium falciparum afforded by G6PD deficiency. Specifically, he quotes data from a study (Ruwende et al., 1995) conducted in Gambia and in Kenya, from which it was claimed that the degree of protection was similar in ...
openaire +2 more sources
This study combining network pharmacology with molecular docking further confirmed via in vitro experiments that HED potentiates the anti‐tumor effect of sorafenib in HCC cells through the downregulation of SLC7A11 expression and the induction of ferroptosis.
Hai‐mei Jiang +5 more
wiley +1 more source
ABSTRACT Background and Aims Anemia remains a major contributor to pediatric morbidity and mortality in sub‐Saharan Africa, yet contemporary data from tertiary pediatric emergency settings are limited, particularly among children older than 5 years. This study assessed the prevalence, factors associated with anemia, hematological characteristics, and ...
Serwah Bonsu Asafo‐Agyei +4 more
wiley +1 more source
Abstract Objectives This study evaluates the association of low‐dose aspirin (LDA) with hemoglobin (Hb) levels during pregnancy and explores how changes in Hb levels relate to hypertensive disorders of pregnancy (HDP). Methods This secondary analysis of a randomized controlled trial comprised 249 pregnant women recruited from a regional hospital in ...
N. M. Ngcobo +4 more
wiley +1 more source

