Results 21 to 30 of about 1,019,197 (220)

Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency in Neonates Presenting with Indirect Hyperbilirubinemia

Journal of the Dow University of Health Sciences, 2022
Objective: To determine the frequency of glucose-6-phosphate dehydrogenase (G6PD) deficiency in neonates presenting with indirect hyperbilirubinemia. Methods: A prospective cross-sectional study was conducted at Neonatal intensive care unit (NICU) of ...
Ajea Rani, Mashal Khan
doaj   +1 more source

Severe G6PD deficiency leads to recurrent infections and defects in ROS production: Case report and literature review

Frontiers in Genetics, 2022
Purpose: Severe glucose-6-phosphate dehydrogenase (G6PD) deficiency can lead to reduced nicotinamide adenine dinucleotide phosphate oxidase activity in phagocytes, resulting in immunodeficiency, with a limited number of reported cases.
Bijun Sun, Qifan Li, Xiaolong Dong, J. Hou, Wenjie Wang, W. Ying, X. Hui, Qinhua Zhou, Haili Yao, Jinqiao Sun, Xiaochuan Wang   +10 more
semanticscholar   +1 more source

The ethnogeographic variability of genetic factors underlying G6PD deficiency.

Pharmacological Research, 2021
Glucose-6-phosphate dehydrogenase (G6PD) deficiency caused by genetic variants in the G6PD gene, constitutes the most common enzymopathy worldwide affecting approximately 5% of the global population.
M. Koromina, Maria-Theodora Pandi, P. J. van der Spek, G. Patrinos, Volker M. Lauschke   +4 more
semanticscholar   +1 more source

G6PD deficiency, redox homeostasis, and viral infections: implications for SARS-CoV-2 (COVID-19)

Free radical research, 2021
The COVID-19 pandemic has so far affected more than 45 million people and has caused over 1 million deaths worldwide. Infection with SARS-CoV-2, the pathogenic agent, which is associated with an imbalanced redox status, causes hyperinflammation and a ...
Hung-chi Yang, Tian-Hsiang Ma, W. Tjong, A. Stern, D. Chiu   +4 more
semanticscholar   +1 more source

Prevalence of and mothers’ knowledge, attitude and practice towards glucose-6-phosphate dehydrogenase deficiency among neonates with jaundice: a cross-sectional study

BMJ Open, 2020
BackgroundNeonatal jaundice (NNJ) is a frequent complication of glucose-6-phosphate dehydrogenase (G6PD) deficiency.ObjectivesTo estimate the prevalence of G6PD deficiency among neonates with jaundice and to assess mothers’ perception towards G6PD and ...
Zeinab A Kasemy, Wael A Bahbah, Sally M El Hefnawy, Safa H Alkalash   +3 more
doaj   +1 more source

Reference and point-of-care testing for G6PD deficiency: Blood disorder interference, contrived specimens, and fingerstick equivalence and precision

PLoS ONE, 2021
Certain clinical indications and treatments such as the use of rasburicase in cancer therapy and 8-aminoquinolines for Plasmodium vivax malaria treatment would benefit from a point-of-care test for glucose-6-phosphate dehydrogenase (G6PD) deficiency ...
S. Pal, Jane Myburgh, P. Bansil, A. Hann, L. Robertson, E. Gerth-Guyette, G. Ambler, G. Bizilj, M. Kahn, S. Zobrist, Michelle R Manis, Nickolas A Styke, Vajra Allan, Richard Ansbro, Tobilola Akingbade, A. Bryan, S. Murphy, J. Kublin, M. Layton, G. Domingo   +19 more
semanticscholar   +1 more source

Fine mapping of Glucose 6 Phosphate Dehydrogenase (G6PD) deficiency in rural area of South West Odisha using the clinical, hematological and molecular approach

Mediterranean Journal of Hematology and Infectious Diseases, 2020
Introduction: The aim of the study was to enumerate the clinical, hematological and molecular spectrum of G6PD deficiency in malaria endemic regions of south west Odisha.
Ravindra Kumar, MPSS Singh, Soumendu Mahapatra, Sonam Chourasia, Malay Kumar Tripathi, John Oommen, Praveen Kumar Bharti, Rajasubramaniam Shanmugam   +7 more
doaj   +1 more source

Newborn Screening for G6PD Deficiency in Xiamen, China: Prevalence, Variant Spectrum, and Genotype-Phenotype Correlations

Frontiers in Genetics, 2021
Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common inherited enzymatic defect. The purpose of this study was to evaluate the profile of G6PD deficiency and investigate the factors associated with the accuracy of newborn screening
Xudong Wang, Zhongmin Xia, Ying He, Xiaoman Zhou, Haixia Zhang, C. Gao, Yun-sheng Ge, Xiaofang Cai, Yulin Zhou, Qiwei Guo   +9 more
semanticscholar   +1 more source

Real-life implementation of a G6PD deficiency screening qualitative test into routine vivax malaria diagnostic units in the Brazilian Amazon (SAFEPRIM study)

PLoS Neglected Tropical Diseases, 2021
Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency greatly hinders Plasmodium vivax malaria radical cure and further elimination due to 8-aminoquinolines-associated hemolysis.
J. Brito-Sousa, F. Murta, Sheila Vitor-Silva, V. Sampaio, Maxwell O Mendes, Marcelo Brito, T. Batista, A. Santos, Leonardo L G Marques, Laila R A Barbosa, M. Melo, D. Baía-da-Silva, A. Silva-Neto, T. Santos, Brenda K A Souza, E. F. Figueiredo, Emanuelle Silva, Sheila Rodovalho, T. Nakagawa, A. Arcanjo, A. Siqueira, G. Melo, Judith Recht, G. Domingo, Q. Bassat, G. Bancone, W. Monteiro, M. Lacerda   +27 more
semanticscholar   +1 more source

Distribution of G6PD deficiency genotypes among Southeast Asian populations

Tropical Medicine and Health, 2021
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a group of X-linked, hereditary genetic disorders caused by mutations in the G6PD gene and results in functional variants of about 400 biochemical and clinical phenotypes.
I. Tantular, F. Kawamoto
semanticscholar   +1 more source