Results 61 to 70 of about 23,995 (263)

Co-inheritance of glucose-6-phosphate dehydrogenase deficiency mutations and hemoglobin E in a Kachin population in a malaria-endemic region of Southeast Asia.

open access: yesPLoS ONE, 2017
Glucose-6-phosphate dehydrogenase (G6PD) deficiency and hemoglobin E (HbE, β26 Glu-Lys) are two common red cell disorders in Southeast Asia. G6PD deficiency produces hemolytic anemia, which can be triggered by certain drugs or infections.
Zeshuai Deng   +11 more
doaj   +1 more source

Emerging role of the pentose phosphate pathway in hepatocellular carcinoma [PDF]

open access: yes, 2017
In recent years, there has been a revival of interest in metabolic changes of cancer cells as it has been noticed that malignant transformation and metabolic reprogramming are closely intertwined.
Columbano, Amedeo   +2 more
core   +2 more sources

G6PD deficiency and malaria selection [PDF]

open access: yesHeredity, 2011
In his valuable review on genetics of malaria resistance, Hedrick (2011) tackles the interesting issue of the protection against Plasmodium falciparum afforded by G6PD deficiency. Specifically, he quotes data from a study (Ruwende et al., 1995) conducted in Gambia and in Kenya, from which it was claimed that the degree of protection was similar in ...
openaire   +2 more sources

Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila

open access: yesAdvanced Science, EarlyView.
Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu   +7 more
wiley   +1 more source

The Impact of Glucose-6-Phosphate Dehydrogenase Deficiency on the Frequency of Vasoocclusive Crisis in Patients with Sickle Cell Anemia

open access: yesPlasmatology, 2021
Background and Objectives Sickle cell anemia (SCA) and glucose-6-phosphate dehydrogenase (G6PD) deficiency are both hereditary diseases of the red blood cells that cause hemolysis.
Hilary Nnamezie Igwilo   +2 more
doaj   +1 more source

Deficiência de glicose-6-fosfato desidrogenase eritrocitária em recém-nascidos do sexo masculino e sua relação com a icterícia neonatal [PDF]

open access: yes, 2010
Glucose-6-phosphate dehydrogenase (G6PD) deficiency, the commonest red cell enzymopathy in humans, has an X-linked inheritance. The major clinical manifestations are drug induced hemolytic anemia, neonatal jaundice and chronic nonspherocytic hemolytic ...
AMORIM, Maria do Socorro T.   +6 more
core   +1 more source

G6PD Deficiency in Neonatal Jaundice

open access: yesVan Medical Journal, 2022
INTRODUCTION: Neonatal jaundice is one of the important problems encountered by the newborn in the first week after birth, the etiology of which is very diverse and sometimes no cause can be detected. It can result in death if the patients differ in their clinics and are not diagnosed early. Glucose-6-phosphate dehydrogenase (G6PD) deficiency, which is
Altay Babacan   +2 more
openaire   +2 more sources

Biomimetic Cell Membrane‐Coated MOFs System for Targeted Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Biomimetic MOF‐based drug delivery nanoplatforms synthesized using liposomes or cell membranes as camouflage for multiple cancer therapeutics. ABSTRACT The integration of metal‐organic frameworks (MOFs) with cell membrane coatings has emerged as a revolutionary strategy to enhance the therapeutic efficacy of cancer nanomedicine.
Qilu Wu   +6 more
wiley   +1 more source

Evaluation of the diagnostic accuracy of CareStart G6PD deficiency Rapid Diagnostic Test (RDT) in a malaria endemic area in Ghana, Africa.

open access: yesPLoS ONE, 2015
BackgroundGlucose-6-phosphate dehydrogenase (G6PD) deficiency is the most widespread enzyme defect that can result in red cell breakdown under oxidative stress when exposed to certain medicines including antimalarials.
Dennis Adu-Gyasi   +12 more
doaj   +1 more source

Inherited hemolytic disorders with high occurrence of b-thalassemia in Sindhi community of Jabalpur town in Madhya Pradesh, India [PDF]

open access: yes, 2010
Hereditary hemolytic disorders such as hemoglobin disorders, β-thalassemia syndrome, G6PD deficiency, and ABO and Rhesus blood groups are the most common public health problems in India.
Balgir, RS
core   +1 more source

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