Results 81 to 90 of about 1,989,070 (268)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Technology enhanced interaction framework [PDF]

open access: yes, 2013
This paper focuses on the development of a general interaction framework to help design technology to support communication between people and improve interactions between people, technology and objects, particularly in complex situations.
Lester Gilbert   +5 more
core   +1 more source

Genotype × environment interactions and stability analysis for grain yield in pearl millet [Pennisetum glaucum (L.) R. BR.]

open access: yesElectronic Journal of Plant Breeding
The present investigation was carried out at Regional Research Station, Anand Agricultural University, Anand during the years 2019-20 to 2020-21 to study the phenotypic stability for grain yield in pearl millet genotypes.
A. L. Patel1*, D. A. Patel2, Rumit Patel3, D. J. Parmar4 and Kalyanrao Patil5
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Visual cognition during real social interaction [PDF]

open access: yes, 2012
Copyright @ 2012 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and 85 reproduction in any medium, provided the original author and source
Skarratt, PA, Kuhn, G, Cole, GG
core   +1 more source

Alternative breeding processes: at which extent Participatory Breeding should modify the concept of ideotypes in plant breeding?

open access: yesOilseeds and fats, crops and lipids, 2018
The Participatory Plant Breeding (PPB) concept emerged twenty years ago, particularly with the aim to build alternative organizations of the plant breeding activities in developing countries. It now as well questions the developed countries, in the frame
Vincourt Patrick, Carolo Pierre
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Using polygenic scores to assess liability to antisocial behavior

open access: yesВавиловский журнал генетики и селекции
To date, several genome-wide association studies (GWAS) of antisocial behavior (ASB) have been conducted in Europeans, which promoted research aimed at evaluating liability to ASB-related phenotypes in independent samples.
A. V. Kazantseva   +3 more
doaj   +1 more source

Genotype x environment interaction for fruit yield and component characters in okra [Abelmoschus esculentus (L.) Moench]

open access: yesElectronic Journal of Plant Breeding, 2017
With prime objective of developing season/region specific as well as stable hybrids of okra [Abelmoschus esculentus (L.) Moench], the present investigation was undertaken with thirty-seven entries viz., eight parents, twenty eight F1’s and one standard ...
Sunil Suresh Patil   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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