Results 151 to 158 of about 5,197 (158)

Synthesis of a photoreactive, radiolabelled derivative of the oligosaccharide of G_M1 ganglioside

Glycobiology, 1992
A photoreactive, radioiodinatable derivative of the oligosaccharide (GM1OS) of ganglioside GM1 was synthesized as follows: GM1OS was generated from GM1 by ozonolysis and alkaline fragmentation, and reductively aminated to GM1OSNH2 (1-amino-1-deoxymonosialogangliotetraitol).
T, Pacuszka, P H, Fishman
openaire   +2 more sources

An Immunological Model of Epilepsy: Seizures Induced by Antibodies to G_M1 Ganglioside

Epilepsia, 1981
Summary: Following observations that the intracerebral injection into rats of antiserum to brain gangliosides resulted in recurrent epileptiform activity and that seizure activity was not seen if antibodies were removed by absorption of the antiserum with pure GM1 ganglioside, a study was undertaken to establish characteristics of the immunological ...
S E, Karpiak, S P, Mahadik, L, Graf, M M, Rapport   +3 more
openaire   +2 more sources

Antibodies to ganglioside G_M1 induce mitogenic stimulation and cap formation in rat thymocytes

European Journal of Immunology, 1978
AbstractAntibodies towards the ganglioside GM1[galactosyl‐N‐acetylgalactosaminyl‐(N‐acetylneuraminyl)‐galactosylglucosyl ceramide] stimulated DNA synthesis in rat thymocytes. No mitogenic stimulation was observed with the monomeric Fab fragment of anti‐GM1, suggesting that cross‐linking of the gangliosides or associated components was required for ...
B A, Sela, A, Raz, B, Geiger
openaire   +2 more sources

Detection of α‐Glycosidic Bonds in the Ganglioside G_M1 by Stereospecific Enzymatic Degradation

European Journal of Biochemistry, 1973
The monosialosyl‐N‐tetraglycosyl‐ceramide (GM1) isolated from ox brain and submitted to a stepwise degradation by specific α‐ and β‐glycosidases isolated and purified from ox spleen. By the sequential action of β‐galactosidase and β‐N‐acetylhexosaminidase, 100% of the terminal galactose and the N‐acetylgalactosamine residues were removed, while the ...
E, Werries, E, Buddecke
openaire   +2 more sources

Biodistribution and Antitumor Effect of Adriamycin Encapsulated in Long-Circulating Liposomes Containing Amphipathic Polyethylene Glycol or Ganglioside G_M1

Journal of Liposome Research, 1994
AbstractBiodistribution and antitumor effect of adriamycin (ADM) encapsulated in liposomes with reduced uptake by reticuloendothelial system (RES) and prolonged circulation time were investigated in mice. Two different types of long-circulating liposomes, ganglioside GMI (GMl)/distearoyl phosphatidyl choline (DSPC) /cholesterol (CH) (0.13:1:1, m/m) and
Kazuo Maruyama, Aki Okamoto, Osamu Ishida, Shuji Kojima, Akinori Suginaka, Leaf Huang, Motohary Iwatsuru   +6 more
openaire   +1 more source

Fixation and Inactivation of Staphylococcal Leukocidin by Phosphatidylcholine and Ganglioside G _M1 in Rabbit Polymorphonuclear Leukocytes

Infection and Immunity, 1980
Staphylococcal leukocidin is resolved by chromatography on carboxymethyl cellulose columns into two components, which are designated F (fast) and S (slow). Fixation and inactivation of both components were studied as follows. (i) Leukocidin activity was confined to the first 10 min of intoxication, and the maximal effect resulted from ...
M, Noda, I, Kato, T, Hirayama, F, Matsuda   +3 more
openaire   +2 more sources

Characterization of the binding of cholera toxin to ganglioside G_M1 immobilized onto microtitre plates

Journal of Applied Toxicology, 2005
AbstractGanglioside GM1 is the receptor for cholera toxin on cell surfaces, and the binding of cholera toxin to GM1 immobilized on microtitre plates has been reported previously by several authors as an assay for the toxin (GM1‐ELISA). This assay has been examined in detail.
openaire   +2 more sources

Growth inhibition by cholera toxin of human lung carcinoma cell lines: Correlation with G(M1) ganglioside expression

Lung Cancer, 1993
G Kaur, J Viallet, J Laborda, O Blair, AF Gazdar, JD Minna   +5 more
openaire   +1 more source